Abstract
In a recent report, Grome et al. describe a genomically recoded Escherichia coli strain with a 62-codon genome and a single stop codon. This and other genomically recoded organisms (GROs), engineered with modified genetic vocabularies, enable the creation of novel proteins and biomaterials, while ensuring the safety and viability of GRO-based biomanufacturing.
| Original language | English |
|---|---|
| Pages (from-to) | 993-995 |
| Number of pages | 3 |
| Journal | Trends in Biotechnology |
| Volume | 43 |
| Issue number | 5 |
| DOIs | |
| State | Published - 1 May 2025 |
Keywords
- biocontainment
- genomically recoded organisms
- noncanonical amino acids
- orthogonal translation machinery
ASJC Scopus subject areas
- Biotechnology
- Bioengineering
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