Genetic and Mechanical Regulation of Intestinal Smooth Muscle Development

Tyler R. Huycke; Bess M. Miller; Hasreet K. Gill; Nandan L. Nerurkar; David Sprinzak; L. Mahadevan; Clifford J. Tabin

doi:https://doi.org/10.1016/j.cell.2019.08.041

Genetic and Mechanical Regulation of Intestinal Smooth Muscle Development

Tyler R. Huycke, Bess M. Miller, Hasreet K. Gill, Nandan L. Nerurkar, David Sprinzak, L. Mahadevan, Clifford J. Tabin

Biochemistry Molecular Biology

Tel Aviv University

Research output: Contribution to journal › Article › peer-review

Abstract

Gut smooth muscle patterning entails mechanical strain that orients the first layer circumferentially, and when formed, it spontaneously contracts to align the second layer longitudinally.

Original language	English
Pages (from-to)	90-105.e21
Journal	Cell
Volume	179
Issue number	1
DOIs	https://doi.org/10.1016/j.cell.2019.08.041
State	Published - 19 Sep 2019

Keywords

Bmp
Hedgehog
cell orientation
differentiation
gut development
mechanical forces
morphogenesis
patterning
smooth muscle

All Science Journal Classification (ASJC) codes

General Biochemistry,Genetics and Molecular Biology

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https://doi.org/10.1016/j.cell.2019.08.041

Cite this

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title = "Genetic and Mechanical Regulation of Intestinal Smooth Muscle Development",

abstract = "Gut smooth muscle patterning entails mechanical strain that orients the first layer circumferentially, and when formed, it spontaneously contracts to align the second layer longitudinally.",

keywords = "Bmp, Hedgehog, cell orientation, differentiation, gut development, mechanical forces, morphogenesis, patterning, smooth muscle",

author = "Huycke, {Tyler R.} and Miller, {Bess M.} and Gill, {Hasreet K.} and Nerurkar, {Nandan L.} and David Sprinzak and L. Mahadevan and Tabin, {Clifford J.}",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",

year = "2019",

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day = "19",

doi = "https://doi.org/10.1016/j.cell.2019.08.041",

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T1 - Genetic and Mechanical Regulation of Intestinal Smooth Muscle Development

AU - Huycke, Tyler R.

AU - Miller, Bess M.

AU - Gill, Hasreet K.

AU - Nerurkar, Nandan L.

AU - Sprinzak, David

AU - Mahadevan, L.

AU - Tabin, Clifford J.

PY - 2019/9/19

Y1 - 2019/9/19

N2 - Gut smooth muscle patterning entails mechanical strain that orients the first layer circumferentially, and when formed, it spontaneously contracts to align the second layer longitudinally.

AB - Gut smooth muscle patterning entails mechanical strain that orients the first layer circumferentially, and when formed, it spontaneously contracts to align the second layer longitudinally.

KW - Bmp

KW - Hedgehog

KW - cell orientation

KW - differentiation

KW - gut development

KW - mechanical forces

KW - morphogenesis

KW - patterning

KW - smooth muscle

UR - http://www.scopus.com/inward/record.url?scp=85071987128&partnerID=8YFLogxK

U2 - https://doi.org/10.1016/j.cell.2019.08.041

DO - https://doi.org/10.1016/j.cell.2019.08.041

M3 - مقالة

SN - 0092-8674

VL - 179

SP - 90-105.e21

JO - Cell

JF - Cell

IS - 1

ER -

Genetic and Mechanical Regulation of Intestinal Smooth Muscle Development

Abstract

Keywords

All Science Journal Classification (ASJC) codes

Access to Document

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