Functional evaluation of autism-associated mutations in NHE9

Biochemistry, Genetics and Molecular Biology

• Astrocyte 100%
• Neurotransmitter 100%
• Protein Expression 50%
• Missense 50%
• Candidate Gene 50%
• Glutamic Acid 50%
• Crystal Structure 50%
• Loss of Function Mutation 50%
• Membrane Protein 50%
• Genetic Conservation 50%
• Transferrin 50%
• Transferrin Receptor 50%
• Synaptic Membrane 50%
• Antiporter 50%

Keyphrases

• Autism 100%
• Functional Assessment 100%
• NHE9 100%
• Neurotransmitters 33%
• Gain-of-function mutation 16%
• Glutamate 16%
• Astrocytes 16%
• Surface Expression 16%
• Functional Analysis 16%
• Human Population 16%
• Transferrin 16%
• GLAST 16%
• Orthologues 16%
• Evolutionary Conservation 16%
• Endosomal 16%
• Autistic Traits 16%
• Transferrin Receptor 1 (TfR1) 16%
• Conservation Analysis 16%
• Recycling Endosome 16%
• Membrane Protein Expression 16%
• NhaA 16%
• Missense Substitution 16%
• Cation-proton Antiporters 16%
• SLC9A9 16%
• Luminal pH 16%
• Synaptic Membrane Protein 16%
• Primary Cortical Astrocytes 16%