Full scattering profile for detecting physiological tissue properties

Hamootal Duadi, Dror Fixler

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Light reflectance and transmission from soft tissue has been utilized in noninvasive clinical measurement devices such as the photoplethysmograph (PPG) and reflectance pulse oximeter. Most methods of near infrared (NIR) spectroscopy focus on the volume reflectance from a semi-infinite sample, while very few measure transmission. We have previously shown that examining the full scattering profile (FSP), which is the angular distribution of exiting photons, provides more comprehensive information when measuring from a cylindrical tissue, such as earlobe, fingertip and pinched tissue. Our hypothesis is that the change in blood vessel diameter is more significant than the change in optical properties. The findings of this work demonstrate a realistic model for optical tissue measurements such as NIR spectroscopy, PPG and pulse oximetery.

Original languageEnglish
Title of host publicationNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIV
EditorsDan V. Nicolau, Dror Fixler, Alexander N. Cartwright
PublisherSPIE
ISBN (Electronic)9781510605954
DOIs
StatePublished - 2017
EventNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIV 2017 - San Francisco, United States
Duration: 30 Jan 20171 Feb 2017

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10077

Conference

ConferenceNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIV 2017
Country/TerritoryUnited States
CitySan Francisco
Period30/01/171/02/17

Keywords

  • Light tissue interactions
  • Monte Carlo simulation
  • Multiple scattering
  • Photon migration

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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