Fluorescence depolarization studies of heteroatom-doped CDs

Manoop Chenchiliyan, Hari Krishna Sadhanala, Kusha Sharma, Alix Le Marois, Aharon Gedanken, Dror Fixler

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

In this work, we exploited time-resolved fluorescence polarization anisotropy (TRFA) to characterize un-doped and doped carbon dots (CDs). The rotational correlation time related to the size of the particle through classical Stokes-Einstein-Debye equation. The TRFA technique applied in this study achieves picoseconds time resolution, which approximately corresponds to the particle size determination at sub-nanometer precision. The calculated diameter of the CDs from the measured depolarization time constants in aqueous solution is well matches with the actual size of the CDs within the precision. This study proves that the TRFA method is highly complementary with other size determination techniques.

Original languageEnglish
Title of host publicationNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVI
EditorsDan V. Nicolau, Dror Fixler, Ewa M. Goldys
PublisherSPIE
ISBN (Electronic)9781510624245
DOIs
StatePublished - 2019
EventNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVI 2019 - San Francisco, United States
Duration: 3 Feb 20194 Feb 2019

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10891

Conference

ConferenceNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVI 2019
Country/TerritoryUnited States
CitySan Francisco
Period3/02/194/02/19

Keywords

  • Carbon dots
  • Fluorescence anisotropy
  • Hydrodynamic diameter
  • Nanoparticle sizing

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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