Flipping interferometry and its application for quantitative phase microscopy in a micro-channel

Darina Roitshtain, Nir A. Turko, Bahram Javidi, Natan T. Shaked

Research output: Contribution to journalArticlepeer-review

Abstract

We present a portable, off-axis interferometric module for quantitative phase microscopy of live cells, positioned at the exit port of a coherently illuminated inverted microscope. The module creates on the digital camera an interference pattern between the image of the sample and its flipped version. The proposed simplified module is based on a retro-reflector modification in an external Michelson interferometer. The module does not contain any lenses, pinholes, or gratings and its alignment is straightforward. Still, it allows full control of the off-axis angle and does not suffer from ghost images. As experimentally demonstrated, the module is useful for quantitative phase microscopy of live cells rapidly flowing in a micro-channel.

Original languageEnglish
Pages (from-to)2354-2357
Number of pages4
JournalOptics Letters
Volume41
Issue number10
DOIs
StatePublished - 15 May 2016

All Science Journal Classification (ASJC) codes

  • Atomic and Molecular Physics, and Optics

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