Endoscope-based scattering measurements of esophagus phantoms

Natanel Ovadia, Hamootal Duadi, Dror Fixler

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

In today's medical world, endoscopy is one of the most common methods for assessing a patient's health status, yet in most cases, endoscopy is not sufficient and usually requires other examinations as well. It is widely known that healthy, and diseased tissues possess different optical properties like scattering and absorption. By finding the changes in those optical properties it's possible to determine the tissue status by endoscopy only. This poster suggests an alternative self-calibrated endoscopy examination for finding these properties and quantitatively assessing the tissue. Implementing the physical phenomenon called the iso pathlength (IPL) point, makes it possible to extract the tissue absorption property since it simplifies the problem into an easily solvable first-order problem. The phenomenon claims the existence of physical positions on the surface tissue, in which the light reflected from, isn't affected by the tissue's scattering. The work proves experimentally the existence of the IPL point for hollow cylindrical tissue structures. Three hollow cylindrical phantoms, with different scattering coefficients and negligible absorption properties, were illuminated, and by extracting all the reflected intensities of the different phantoms as a function of length or angle, a cross point between all the variables was shown. This spot proves the existence of points that aren't affected by the scattering profile.

Original languageEnglish
Title of host publicationNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XXI
EditorsDror Fixler, Sebastian Wachsmann-Hogiu
PublisherSPIE
ISBN (Electronic)9781510669758
DOIs
StatePublished - 2024
EventNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XXI 2024 - San Francisco, United States
Duration: 28 Jan 2024 → …

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume12858

Conference

ConferenceNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XXI 2024
Country/TerritoryUnited States
CitySan Francisco
Period28/01/24 → …

Keywords

  • Diffusion reflection
  • Endoscopy
  • Light-Tissue interaction.
  • Phantoms
  • Scattering
  • The iso pathlength point (IPL)

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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