ELECTROKINETICALLY SEPARATING, ENCAPSULATING AND EXTRACTING ANALYTES ON A MICROFLUIDIC DEVICE

Govind Kaigala (Inventor), Federico Paratore (Inventor), Onur Gökçe (Inventor), Moran Bercovici (Inventor), Xander Van Kooten (Inventor)

Research output: Patent

Abstract

Embodiments of the invention are directed to a method of separating and encapsulating an analyte on a microfluidic device in order to extract the analyte. A microfluidic device is provided having a main microchannel and a set of one or more auxiliary microchannels, each branching to the main microchannel at respective junctions therewith. A mixture is introduced as a single phase in the main microchannel in order to electrokinetically separate an analyte from the introduced mixture, and in order to confine the separated analyte in a microchannel portion of the main microchannel. The microchannel portion adjoins one of the junctions. One or more encapsulating volumes of an encapsulating phase are injected in the main microchannel via one or more of the auxiliary microchannels. The encapsulating phase is immiscible with said single phase. The encapsulated analyte is extracted from the main microchannel via one or more of the auxiliary microchannels.

Original languageAmerican English
Patent numberUS2020061616
IPCB01L 3/ 00 A I
Priority date22/08/18
StatePublished - 27 Feb 2020

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