Electrochemically stimulated drug release from flexible electrodes coated electrophoretically with doxorubicin loaded reduced graphene oxide

Lijie He; Sujoy Sarkar; Alexandre Barras; Rabah Boukherroub; Sabine Szunerits; Daniel Mandler

doi:10.1039/c7cc00381a

Electrochemically stimulated drug release from flexible electrodes coated electrophoretically with doxorubicin loaded reduced graphene oxide

Lijie He, Sujoy Sarkar, Alexandre Barras, Rabah Boukherroub, Sabine Szunerits, Daniel Mandler

Institute of Chemistry

The Hebrew University of Jerusalem

Research output: Contribution to journal › Article › peer-review

Abstract

The electrochemically triggered release of doxorubicin (DOX) from flexible electrodes modified electrophoretically with reduced graphene oxide (rGO)-DOX is reported. The release is driven by a positive potential pulse that decreases the pH of the rGO-DOX surface locally, which is confirmed by scanning electrochemical microscopy (SECM) in situ. In vitro cell viability tests confirms that the delivery system meets therapeutic needs.

Original language	English
Pages (from-to)	4022-4025
Number of pages	4
Journal	Chemical Communications
Volume	53
Issue number	28
DOIs	https://doi.org/10.1039/c7cc00381a
State	Published - 2017

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c7cc00381a

Cite this

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title = "Electrochemically stimulated drug release from flexible electrodes coated electrophoretically with doxorubicin loaded reduced graphene oxide",

abstract = "The electrochemically triggered release of doxorubicin (DOX) from flexible electrodes modified electrophoretically with reduced graphene oxide (rGO)-DOX is reported. The release is driven by a positive potential pulse that decreases the pH of the rGO-DOX surface locally, which is confirmed by scanning electrochemical microscopy (SECM) in situ. In vitro cell viability tests confirms that the delivery system meets therapeutic needs.",

author = "Lijie He and Sujoy Sarkar and Alexandre Barras and Rabah Boukherroub and Sabine Szunerits and Daniel Mandler",

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AU - He, Lijie

AU - Sarkar, Sujoy

AU - Barras, Alexandre

AU - Boukherroub, Rabah

AU - Szunerits, Sabine

AU - Mandler, Daniel

PY - 2017

Y1 - 2017

N2 - The electrochemically triggered release of doxorubicin (DOX) from flexible electrodes modified electrophoretically with reduced graphene oxide (rGO)-DOX is reported. The release is driven by a positive potential pulse that decreases the pH of the rGO-DOX surface locally, which is confirmed by scanning electrochemical microscopy (SECM) in situ. In vitro cell viability tests confirms that the delivery system meets therapeutic needs.

AB - The electrochemically triggered release of doxorubicin (DOX) from flexible electrodes modified electrophoretically with reduced graphene oxide (rGO)-DOX is reported. The release is driven by a positive potential pulse that decreases the pH of the rGO-DOX surface locally, which is confirmed by scanning electrochemical microscopy (SECM) in situ. In vitro cell viability tests confirms that the delivery system meets therapeutic needs.

UR - http://www.scopus.com/inward/record.url?scp=85017105095&partnerID=8YFLogxK

U2 - 10.1039/c7cc00381a

DO - 10.1039/c7cc00381a

M3 - مقالة

C2 - 28338701

SN - 1359-7345

VL - 53

SP - 4022

EP - 4025

JO - Chemical Communications

JF - Chemical Communications

IS - 28

ER -

Electrochemically stimulated drug release from flexible electrodes coated electrophoretically with doxorubicin loaded reduced graphene oxide

Abstract

UN SDGs

All Science Journal Classification (ASJC) codes

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