Electrochemically stimulated drug release from flexible electrodes coated electrophoretically with doxorubicin loaded reduced graphene oxide

Lijie He, Sujoy Sarkar, Alexandre Barras, Rabah Boukherroub, Sabine Szunerits, Daniel Mandler

Research output: Contribution to journalArticlepeer-review

Abstract

The electrochemically triggered release of doxorubicin (DOX) from flexible electrodes modified electrophoretically with reduced graphene oxide (rGO)-DOX is reported. The release is driven by a positive potential pulse that decreases the pH of the rGO-DOX surface locally, which is confirmed by scanning electrochemical microscopy (SECM) in situ. In vitro cell viability tests confirms that the delivery system meets therapeutic needs.

Original languageEnglish
Pages (from-to)4022-4025
Number of pages4
JournalChemical Communications
Volume53
Issue number28
DOIs
StatePublished - 2017

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • General Chemistry
  • Ceramics and Composites
  • Metals and Alloys
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Catalysis

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