Ectoine biosynthesis in Mycobacterium smegmatis

Naomi Ofer, Marina Wishkautzan, Michael Meijler, Ying Wang, Alexander Speer, Michael Niederweis, Eyal Gur

Research output: Contribution to journalArticlepeer-review


Mycobacterium smegmatis is a commonly used mycobacterial model system. Here, we show that M. smegmatis protects itself against elevated salinity by synthesizing ectoine and hydroxyectoine and characterize the phenotype of a nonproducing mutant. This is the first analysis of M. smegmatis halotolerance and of the molecular mechanism that supports it.

Original languageAmerican English
Pages (from-to)7483-7486
Number of pages4
JournalApplied and Environmental Microbiology
Issue number20
StatePublished - 1 Oct 2012

All Science Journal Classification (ASJC) codes

  • Applied Microbiology and Biotechnology
  • Food Science
  • Biotechnology
  • Ecology


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