Ectoine biosynthesis in Mycobacterium smegmatis

Naomi Ofer; Marina Wishkautzan; Michael Meijler; Ying Wang; Alexander Speer; Michael Niederweis; Eyal Gur

doi:10.1128/AEM.01318-12

Ectoine biosynthesis in Mycobacterium smegmatis

Naomi Ofer, Marina Wishkautzan, Michael Meijler, Ying Wang, Alexander Speer, Michael Niederweis, Eyal Gur

Ben-Gurion University of the Negev

Research output: Contribution to journal › Article › peer-review

Abstract

Mycobacterium smegmatis is a commonly used mycobacterial model system. Here, we show that M. smegmatis protects itself against elevated salinity by synthesizing ectoine and hydroxyectoine and characterize the phenotype of a nonproducing mutant. This is the first analysis of M. smegmatis halotolerance and of the molecular mechanism that supports it.

Original language	American English
Pages (from-to)	7483-7486
Number of pages	4
Journal	Applied and Environmental Microbiology
Volume	78
Issue number	20
DOIs	https://doi.org/10.1128/AEM.01318-12
State	Published - 1 Oct 2012

All Science Journal Classification (ASJC) codes

Applied Microbiology and Biotechnology
Food Science
Biotechnology
Ecology

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AU - Ofer, Naomi

AU - Wishkautzan, Marina

AU - Meijler, Michael

AU - Wang, Ying

AU - Speer, Alexander

AU - Niederweis, Michael

AU - Gur, Eyal

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AB - Mycobacterium smegmatis is a commonly used mycobacterial model system. Here, we show that M. smegmatis protects itself against elevated salinity by synthesizing ectoine and hydroxyectoine and characterize the phenotype of a nonproducing mutant. This is the first analysis of M. smegmatis halotolerance and of the molecular mechanism that supports it.

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JO - Applied and Environmental Microbiology

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Ectoine biosynthesis in Mycobacterium smegmatis

Abstract

All Science Journal Classification (ASJC) codes

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