Drug exposure in pregnancy and heart defects

Ilan Matok; Anna Pupco; Gideon Koren

doi:10.1097/FJC.0b013e31821c471b

Drug exposure in pregnancy and heart defects

Ilan Matok, Anna Pupco, Gideon Koren

Research output: Contribution to journal › Review article › peer-review

Abstract

Being the most common group of congenital malformations, congenital heart defects have often been investigated to rule out teratogenic effects by medicinal drugs and chemicals. Yet, the use of rigorous epidemiological methods has rejected such claims in many cases. We critically evaluate drugs believed to be associated with an increased risk of causing congenital heart defects, highlighting the debate and the practical implications of such associations.

Original language	English
Pages (from-to)	20-24
Number of pages	5
Journal	Journal of Cardiovascular Pharmacology
Volume	58
Issue number	1
DOIs	https://doi.org/10.1097/FJC.0b013e31821c471b
State	Published - Jul 2011
Externally published	Yes

Keywords

cardiac birth defects
congenital malformations
drugs safety
pregnancy

All Science Journal Classification (ASJC) codes

Cardiology and Cardiovascular Medicine
Pharmacology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1097/FJC.0b013e31821c471b

Cite this

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abstract = "Being the most common group of congenital malformations, congenital heart defects have often been investigated to rule out teratogenic effects by medicinal drugs and chemicals. Yet, the use of rigorous epidemiological methods has rejected such claims in many cases. We critically evaluate drugs believed to be associated with an increased risk of causing congenital heart defects, highlighting the debate and the practical implications of such associations.",

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AU - Matok, Ilan

AU - Pupco, Anna

AU - Koren, Gideon

PY - 2011/7

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AB - Being the most common group of congenital malformations, congenital heart defects have often been investigated to rule out teratogenic effects by medicinal drugs and chemicals. Yet, the use of rigorous epidemiological methods has rejected such claims in many cases. We critically evaluate drugs believed to be associated with an increased risk of causing congenital heart defects, highlighting the debate and the practical implications of such associations.

KW - cardiac birth defects

KW - congenital malformations

KW - drugs safety

KW - pregnancy

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U2 - 10.1097/FJC.0b013e31821c471b

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M3 - مقالة مرجعية

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JO - Journal of Cardiovascular Pharmacology

JF - Journal of Cardiovascular Pharmacology

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ER -

Drug exposure in pregnancy and heart defects

Abstract

Keywords

All Science Journal Classification (ASJC) codes

UN SDGs

Access to Document

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