Abstract
Knowledge of immunoglobulin and T cell receptor encoding genes is derived from high-quality genomic sequencing. High-throughput sequencing is delivering large volumes of data, and precise, high-throughput approaches to annotation are needed. Digger is an automated tool that identifies coding and regulatory regions of these genes, with results comparable to those obtained by current expert curational methods. Availability and implementation: Digger is published under open source license at https://github.com/williamdlees/Digger and is available as a Python package and a Docker container.
Original language | English |
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Article number | btae144 |
Journal | Bioinformatics |
Volume | 40 |
Issue number | 3 |
DOIs | |
State | Published - 4 Mar 2024 |
All Science Journal Classification (ASJC) codes
- Computational Mathematics
- Molecular Biology
- Biochemistry
- Statistics and Probability
- Computer Science Applications
- Computational Theory and Mathematics