Development of spinal cord on a microfluidic chip

Jordan Kerns; Norman Wen; Carol Lucchesi; Christopher Hinojosa; Jacob Fraser; Geraldine Hamilton; Gad Vatine; Sam Sances; Clive Svendsen; Daniel Levner

Development of spinal cord on a microfluidic chip

Jordan Kerns (Inventor), Norman Wen (Inventor), Carol Lucchesi (Inventor), Christopher Hinojosa (Inventor), Jacob Fraser (Inventor), Geraldine Hamilton (Inventor), Gad Vatine (Inventor), Sam Sances (Inventor), Clive Svendsen (Inventor), Daniel Levner (Inventor)

Department of Physiology and Cell Biology

Ben-Gurion University of the Negev

Research output: Patent

Abstract

The invention relates to culturing brain endothelial cells, and optionally astrocytes and neurons in a fluidic device under conditions whereby the cells mimic the structure and function of the blood brain barrier. Culture of such cells in a microfluidic device, whether alone or in combination with other cells, drives maturation and/or differentiation further than existing systems.

Original language	American English
Patent number	US2018057788
State	Published - 1 Mar 2018

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title = "Development of spinal cord on a microfluidic chip",

abstract = "The invention relates to culturing brain endothelial cells, and optionally astrocytes and neurons in a fluidic device under conditions whereby the cells mimic the structure and function of the blood brain barrier. Culture of such cells in a microfluidic device, whether alone or in combination with other cells, drives maturation and/or differentiation further than existing systems.",

author = "Jordan Kerns and Norman Wen and Carol Lucchesi and Christopher Hinojosa and Jacob Fraser and Geraldine Hamilton and Gad Vatine and Sam Sances and Clive Svendsen and Daniel Levner",

note = "US Patent App. 15/352,289; US2018057788",

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TY - PAT

T1 - Development of spinal cord on a microfluidic chip

AU - Kerns, Jordan

AU - Wen, Norman

AU - Lucchesi, Carol

AU - Hinojosa, Christopher

AU - Fraser, Jacob

AU - Hamilton, Geraldine

AU - Vatine, Gad

AU - Sances, Sam

AU - Svendsen, Clive

AU - Levner, Daniel

N1 - US Patent App. 15/352,289

PY - 2018/3/1

Y1 - 2018/3/1

N2 - The invention relates to culturing brain endothelial cells, and optionally astrocytes and neurons in a fluidic device under conditions whereby the cells mimic the structure and function of the blood brain barrier. Culture of such cells in a microfluidic device, whether alone or in combination with other cells, drives maturation and/or differentiation further than existing systems.

AB - The invention relates to culturing brain endothelial cells, and optionally astrocytes and neurons in a fluidic device under conditions whereby the cells mimic the structure and function of the blood brain barrier. Culture of such cells in a microfluidic device, whether alone or in combination with other cells, drives maturation and/or differentiation further than existing systems.

M3 - Patent

M1 - US2018057788

ER -

Development of spinal cord on a microfluidic chip

Abstract

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