Detection of Human Growth Hormone (hGH) via Cyclodextrin-Promoted Fluorescence Modulation

Anna Z. Haynes, Mindy Levine

Research output: Contribution to journalArticlepeer-review


The ability to detect human growth hormone (hGH) via sensitive, selective, and easy-to-use methods is a high priority research area from a variety of public health, law enforcement, and scientific objectives. Reported herein is the use of cyclodextrin-promoted fluorescence modulation of a high-quantum yield BODIPY fluorophore in the presence of low concentrations of hGH, leading to a system that can detect hGH in concentrations as low as 0.279 µM and with a 96% accuracy in distinguishing different hGH concentrations.

Original languageEnglish
Pages (from-to)1871-1880
Number of pages10
JournalAnalytical Letters
Issue number11
StatePublished - 2021


  • cyclodextrin
  • fluorescence spectroscopy
  • human growth hormone
  • sensors

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Spectroscopy
  • Clinical Biochemistry
  • Biochemistry, medical
  • Electrochemistry


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