TY - JOUR
T1 - Detection of alkylating agents using electrical and mechanical means
AU - Gerchikov, Yulia
AU - Borzin, Elena
AU - Gannot, Yair
AU - Shemesh, Ariel
AU - Meltzman, Shai
AU - Hertzog-Ronen, Carmit
AU - Tal, Shay
AU - Stolyarova, Sara
AU - Nemirovsky, Yael
AU - Tessler, Nir
AU - Eichen, Yoav
PY - 2011
Y1 - 2011
N2 - Alkylating agents are reactive molecules having at least one polar bond between a carbon atom and a good leaving group. These often simple molecules are frequently used in organic synthesis, as sterilizing agents in agriculture and even as anticancer agents in medicine. Unfortunately, for over a century, some of the highly reactive alkylating agents are also being used as blister chemical warfare agents. Being relatively simple to make, the risk is that these will be applied by terrorists as poor people warfare agents. The detection and identification of such alkylating agents is not a simple task because of their high reactivity and simple structure of the reactive site. Here we report on new approaches to the detection and identification of such alkylating agents using electrical (organic field effect transistors) and mechanical (microcantilevers) means.
AB - Alkylating agents are reactive molecules having at least one polar bond between a carbon atom and a good leaving group. These often simple molecules are frequently used in organic synthesis, as sterilizing agents in agriculture and even as anticancer agents in medicine. Unfortunately, for over a century, some of the highly reactive alkylating agents are also being used as blister chemical warfare agents. Being relatively simple to make, the risk is that these will be applied by terrorists as poor people warfare agents. The detection and identification of such alkylating agents is not a simple task because of their high reactivity and simple structure of the reactive site. Here we report on new approaches to the detection and identification of such alkylating agents using electrical (organic field effect transistors) and mechanical (microcantilevers) means.
UR - http://www.scopus.com/inward/record.url?scp=83055182107&partnerID=8YFLogxK
U2 - https://doi.org/10.1088/1742-6596/307/1/012020
DO - https://doi.org/10.1088/1742-6596/307/1/012020
M3 - مقالة من مؤنمر
SN - 1742-6588
VL - 307
JO - Journal of Physics: Conference Series
JF - Journal of Physics: Conference Series
IS - 1
M1 - 012020
T2 - 16th Conference in the Biennial Sensors and Their Applications
Y2 - 12 September 2011 through 14 September 2011
ER -