DELIVERY SYSTEM COMPRISING A PROTEOLYTIC ENZYME OR EFFECTOR THEREOF FOR USE IN A METHOD FOR ORAL TREATMENT AND USES THEREOF

Avraham D Schroeder; Assaf Yosef Zinger; Avishay Herman; Avraham D Schroeder; Assaf Yosef Zinger; Avishay Herman

DELIVERY SYSTEM COMPRISING A PROTEOLYTIC ENZYME OR EFFECTOR THEREOF FOR USE IN A METHOD FOR ORAL TREATMENT AND USES THEREOF

Avraham D Schroeder (Inventor), Assaf Yosef Zinger (Inventor), Avishay Herman (Inventor), Avraham D Schroeder (Inventor), Assaf Yosef Zinger (Inventor), Avishay Herman (Inventor)

Chemical Engineering

Technion - Israel Institute of Technology

Research output: Patent

Abstract

The present disclosure provides a delivery system comprising (i) a physiologically acceptable carrier and (ii) a proteolytic enzyme or effector thereof for use in a method for relaxing fibers within a subject's oral cavity. In some embodiments, the relaxation is for use in tooth manipulation (particularly repositioning). In some embodiments, the method involves the use of the proteolytic enzyme or effector thereof at a concentration effective to cause relaxation of fibers between the tooth's alveolar bone and gingiva while maintaining integrity of the fibers surrounding the tooth. Also disclosed herein are methods for fiber relaxation and/or repositioning of tooth making use of the proteolytic enzyme or effector thereof.

Original language	American English
Patent number	US2017209551
IPC	A61K 9/ 127 A I
Priority date	19/03/15
State	Published - 27 Jul 2017

Cite this

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title = "DELIVERY SYSTEM COMPRISING A PROTEOLYTIC ENZYME OR EFFECTOR THEREOF FOR USE IN A METHOD FOR ORAL TREATMENT AND USES THEREOF",

abstract = "The present disclosure provides a delivery system comprising (i) a physiologically acceptable carrier and (ii) a proteolytic enzyme or effector thereof for use in a method for relaxing fibers within a subject's oral cavity. In some embodiments, the relaxation is for use in tooth manipulation (particularly repositioning). In some embodiments, the method involves the use of the proteolytic enzyme or effector thereof at a concentration effective to cause relaxation of fibers between the tooth's alveolar bone and gingiva while maintaining integrity of the fibers surrounding the tooth. Also disclosed herein are methods for fiber relaxation and/or repositioning of tooth making use of the proteolytic enzyme or effector thereof.",

author = "Schroeder, {Avraham D} and Zinger, {Assaf Yosef} and Avishay Herman and Schroeder, {Avraham D} and Zinger, {Assaf Yosef} and Avishay Herman",

year = "2017",

month = jul,

day = "27",

language = "American English",

type = "Patent",

note = "US2017209551; A61K 9/ 127 A I",

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TY - PAT

T1 - DELIVERY SYSTEM COMPRISING A PROTEOLYTIC ENZYME OR EFFECTOR THEREOF FOR USE IN A METHOD FOR ORAL TREATMENT AND USES THEREOF

AU - Schroeder, Avraham D

AU - Zinger, Assaf Yosef

AU - Herman, Avishay

AU - Schroeder, Avraham D

AU - Zinger, Assaf Yosef

AU - Herman, Avishay

PY - 2017/7/27

Y1 - 2017/7/27

N2 - The present disclosure provides a delivery system comprising (i) a physiologically acceptable carrier and (ii) a proteolytic enzyme or effector thereof for use in a method for relaxing fibers within a subject's oral cavity. In some embodiments, the relaxation is for use in tooth manipulation (particularly repositioning). In some embodiments, the method involves the use of the proteolytic enzyme or effector thereof at a concentration effective to cause relaxation of fibers between the tooth's alveolar bone and gingiva while maintaining integrity of the fibers surrounding the tooth. Also disclosed herein are methods for fiber relaxation and/or repositioning of tooth making use of the proteolytic enzyme or effector thereof.

AB - The present disclosure provides a delivery system comprising (i) a physiologically acceptable carrier and (ii) a proteolytic enzyme or effector thereof for use in a method for relaxing fibers within a subject's oral cavity. In some embodiments, the relaxation is for use in tooth manipulation (particularly repositioning). In some embodiments, the method involves the use of the proteolytic enzyme or effector thereof at a concentration effective to cause relaxation of fibers between the tooth's alveolar bone and gingiva while maintaining integrity of the fibers surrounding the tooth. Also disclosed herein are methods for fiber relaxation and/or repositioning of tooth making use of the proteolytic enzyme or effector thereof.

M3 - Patent

M1 - US2017209551

ER -