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Delivery of minimally dispersed liquid interfaces for sequential surface chemistry using a microfluidic probe

N. Ostromohov, Moran Bercovici, G. V. Kaigala

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

We present a novel method for sequential delivery of reagents to a reaction site with minimal dispersion of their interfaces using the microfluidic probe. To minimize dispersion, we transport the reagents in segmented flow and passively remove the oil phase in close proximity to the apex, allowing only the aqueous phase to reach the surface. We demonstrate two examples of assays: measurements of reaction-kinetics and protein response to localized chemical stimuli on surface.

Original languageEnglish
Title of host publication20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
Pages85-86
Number of pages2
ISBN (Electronic)9780979806490
StatePublished - 2016
Event20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland
Duration: 9 Oct 201613 Oct 2016

Publication series

Name20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016

Conference

Conference20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
Country/TerritoryIreland
CityDublin
Period9/10/1613/10/16

Keywords

  • Microfluidic probe
  • Reaction kinetics
  • Surface chemistry

All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering

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