De Novo Phospholipid Synthesis Promotes Efficient Autophagy

Alexandra Polyansky, Oren Shatz, Zvulun Elazar

Research output: Contribution to journalEditorialpeer-review

Abstract

Autophagy is an intracellular membrane trafficking process responsible for recycling of macromolecules and organelles and overall cell survival under physiological and pathophysiological conditions.1 It is mediated by a distinct set of core autophagic factors termed ATGs together with general intracellular trafficking factors such as SNAREs, tethering complexes, etc. This adaptive process of formation of a de novo double-membrane organelle is induced under different metabolic and stress conditions, including nutrient deprivation, growth factor depletion, infection, and hypoxia. [first paragraph]
Original languageEnglish
Pages (from-to)1011-1012
Number of pages2
JournalBiochemistry
Volume59
Issue number9
Early online date2 Mar 2020
DOIs
StatePublished - 10 Mar 2020

All Science Journal Classification (ASJC) codes

  • Biochemistry

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