Cyclopentane FIT-PNAs: Bright RNA sensors

Odelia Tepper, Hongchao Zheng, Daniel H. Appella, Eylon Yavin

Research output: Contribution to journalArticlepeer-review


Cyclopentane modified FIT-PNA (cpFIT-PNA) probes are reported as highly emissive RNA sensors with the highest reported brightness for FIT-PNAs. Compared to FIT-PNAs, cpFIT-PNAs have improved mismatch discrimination for several pyrimidine-pyrimidine single nucleotide variants (SNVs).

Original languageEnglish
Pages (from-to)540-543
Number of pages4
JournalChemical Communications
Issue number4
StatePublished - 14 Jan 2021

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry


Dive into the research topics of 'Cyclopentane FIT-PNAs: Bright RNA sensors'. Together they form a unique fingerprint.

Cite this