Cyclodextrin-promoted energy transfer for broadly applicable small-molecule detection

Nicole Serio; Chitapom Chanthalyma; Lindsey Prignano; Mindy Levine

doi:10.1080/10610278.2013.860226

Cyclodextrin-promoted energy transfer for broadly applicable small-molecule detection

Nicole Serio, Chitapom Chanthalyma, Lindsey Prignano, Mindy Levine

Research output: Contribution to journal › Article › peer-review

Abstract

Reported herein is the development of non-covalent, proximity-induced energy transfer from small-molecule toxicants to organic fluorophores bound in the cavity of γ-cyclodextrin. This energy transfer occurs with exceptional efficiency for a broad range of toxicants in complex biological media, and is largely independent of the spectral overlap between the donor and acceptor. This generally applicable phenomenon has significant potential in the development of new turn-on detection schemes.

Original language	English
Pages (from-to)	714-721
Number of pages	8
Journal	Supramolecular Chemistry
Volume	26
Issue number	10-12
DOIs	https://doi.org/10.1080/10610278.2013.860226
State	Published - 1 Dec 2014
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Chemistry

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10.1080/10610278.2013.860226

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abstract = "Reported herein is the development of non-covalent, proximity-induced energy transfer from small-molecule toxicants to organic fluorophores bound in the cavity of γ-cyclodextrin. This energy transfer occurs with exceptional efficiency for a broad range of toxicants in complex biological media, and is largely independent of the spectral overlap between the donor and acceptor. This generally applicable phenomenon has significant potential in the development of new turn-on detection schemes.",

author = "Nicole Serio and Chitapom Chanthalyma and Lindsey Prignano and Mindy Levine",

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AU - Chanthalyma, Chitapom

AU - Prignano, Lindsey

AU - Levine, Mindy

PY - 2014/12/1

Y1 - 2014/12/1

N2 - Reported herein is the development of non-covalent, proximity-induced energy transfer from small-molecule toxicants to organic fluorophores bound in the cavity of γ-cyclodextrin. This energy transfer occurs with exceptional efficiency for a broad range of toxicants in complex biological media, and is largely independent of the spectral overlap between the donor and acceptor. This generally applicable phenomenon has significant potential in the development of new turn-on detection schemes.

AB - Reported herein is the development of non-covalent, proximity-induced energy transfer from small-molecule toxicants to organic fluorophores bound in the cavity of γ-cyclodextrin. This energy transfer occurs with exceptional efficiency for a broad range of toxicants in complex biological media, and is largely independent of the spectral overlap between the donor and acceptor. This generally applicable phenomenon has significant potential in the development of new turn-on detection schemes.

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DO - 10.1080/10610278.2013.860226

M3 - مقالة

SN - 1061-0278

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SP - 714

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JO - Supramolecular Chemistry

JF - Supramolecular Chemistry

IS - 10-12

ER -

Cyclodextrin-promoted energy transfer for broadly applicable small-molecule detection

Abstract

All Science Journal Classification (ASJC) codes

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