Cyclodextrin-Promoted Detection of Aromatic Toxicants and Toxicant Metabolites in Urine

Dana J. DiScenza; Lauren Gareau; Nicole Serio; John Roque; Lindsey Prignano; Molly Verderame; Mindy Levine

doi:10.1080/22297928.2016.1210021

Cyclodextrin-Promoted Detection of Aromatic Toxicants and Toxicant Metabolites in Urine

Dana J. DiScenza, Lauren Gareau, Nicole Serio, John Roque, Lindsey Prignano, Molly Verderame, Mindy Levine

Research output: Contribution to journal › Article › peer-review

Abstract

Reported herein is the development of a fluorescence-based detection method for aromatic toxicants and toxicant metabolites in urine, using cyclodextrin-promoted energy transfer to high quantumyield fluorophores. This method distinguishes smoker urine from non-smoker urine, enables highly accurate analyte identification, and leads to micromolar detection limits.

Original language	English
Pages (from-to)	345-353
Number of pages	9
Journal	Analytical Chemistry Letters
Volume	6
Issue number	4
DOIs	https://doi.org/10.1080/22297928.2016.1210021
State	Published - 2016
Externally published	Yes

Keywords

Cyclodextrin
fluorescence spectroscopy
polycyclic aromatic hydrocarbons

All Science Journal Classification (ASJC) codes

General Chemistry
General Materials Science
Pathology and Forensic Medicine

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10.1080/22297928.2016.1210021

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title = "Cyclodextrin-Promoted Detection of Aromatic Toxicants and Toxicant Metabolites in Urine",

abstract = "Reported herein is the development of a fluorescence-based detection method for aromatic toxicants and toxicant metabolites in urine, using cyclodextrin-promoted energy transfer to high quantumyield fluorophores. This method distinguishes smoker urine from non-smoker urine, enables highly accurate analyte identification, and leads to micromolar detection limits.",

keywords = "Cyclodextrin, fluorescence spectroscopy, polycyclic aromatic hydrocarbons",

author = "DiScenza, {Dana J.} and Lauren Gareau and Nicole Serio and John Roque and Lindsey Prignano and Molly Verderame and Mindy Levine",

note = "Publisher Copyright: {\textcopyright} 2016 Har Krishan Bhalla & Sons.",

year = "2016",

doi = "10.1080/22297928.2016.1210021",

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volume = "6",

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journal = "Analytical Chemistry Letters",

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T1 - Cyclodextrin-Promoted Detection of Aromatic Toxicants and Toxicant Metabolites in Urine

AU - DiScenza, Dana J.

AU - Gareau, Lauren

AU - Serio, Nicole

AU - Roque, John

AU - Prignano, Lindsey

AU - Verderame, Molly

AU - Levine, Mindy

PY - 2016

Y1 - 2016

N2 - Reported herein is the development of a fluorescence-based detection method for aromatic toxicants and toxicant metabolites in urine, using cyclodextrin-promoted energy transfer to high quantumyield fluorophores. This method distinguishes smoker urine from non-smoker urine, enables highly accurate analyte identification, and leads to micromolar detection limits.

AB - Reported herein is the development of a fluorescence-based detection method for aromatic toxicants and toxicant metabolites in urine, using cyclodextrin-promoted energy transfer to high quantumyield fluorophores. This method distinguishes smoker urine from non-smoker urine, enables highly accurate analyte identification, and leads to micromolar detection limits.

KW - Cyclodextrin

KW - fluorescence spectroscopy

KW - polycyclic aromatic hydrocarbons

UR - http://www.scopus.com/inward/record.url?scp=85041499053&partnerID=8YFLogxK

U2 - 10.1080/22297928.2016.1210021

DO - 10.1080/22297928.2016.1210021

M3 - مقالة

SN - 2229-7928

VL - 6

SP - 345

EP - 353

JO - Analytical Chemistry Letters

JF - Analytical Chemistry Letters

IS - 4

ER -

Cyclodextrin-Promoted Detection of Aromatic Toxicants and Toxicant Metabolites in Urine

Abstract

Keywords

All Science Journal Classification (ASJC) codes

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