Cu(OTf)2-Catalyzed Pummerer Coupling of β-Ketosulfoxides

Regev Parnes; Hagai Reiss; Doron Pappo

doi:10.1021/acs.joc.7b02708

Cu(OTf)₂-Catalyzed Pummerer Coupling of β-Ketosulfoxides

Regev Parnes, Hagai Reiss, Doron Pappo

Department of Chemistry

Ben-Gurion University of the Negev

Research output: Contribution to journal › Article › peer-review

Abstract

The copper(II) trifluoromethanesulfonate-catalyzed Pummerer reaction of β-ketosulfoxides with 1,3-dicarbonyl compounds or π-nucleophiles such as phenols, arenes, and tetraallylsilane is reported. The mild conditions provide an efficient entry to a novel class of polysubstituted 3-alkylthiofuran and polysubstituted 3-thiobenzofuran heterocycles from readily available materials.

Original language	American English
Pages (from-to)	723-732
Number of pages	10
Journal	Journal of Organic Chemistry
Volume	83
Issue number	2
DOIs	https://doi.org/10.1021/acs.joc.7b02708
State	Published - 19 Jan 2018

All Science Journal Classification (ASJC) codes

Organic Chemistry

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10.1021/acs.joc.7b02708

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abstract = "The copper(II) trifluoromethanesulfonate-catalyzed Pummerer reaction of β-ketosulfoxides with 1,3-dicarbonyl compounds or π-nucleophiles such as phenols, arenes, and tetraallylsilane is reported. The mild conditions provide an efficient entry to a novel class of polysubstituted 3-alkylthiofuran and polysubstituted 3-thiobenzofuran heterocycles from readily available materials.",

author = "Regev Parnes and Hagai Reiss and Doron Pappo",

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AU - Reiss, Hagai

AU - Pappo, Doron

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Y1 - 2018/1/19

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AB - The copper(II) trifluoromethanesulfonate-catalyzed Pummerer reaction of β-ketosulfoxides with 1,3-dicarbonyl compounds or π-nucleophiles such as phenols, arenes, and tetraallylsilane is reported. The mild conditions provide an efficient entry to a novel class of polysubstituted 3-alkylthiofuran and polysubstituted 3-thiobenzofuran heterocycles from readily available materials.

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M3 - Article

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ER -

Cu(OTf)₂-Catalyzed Pummerer Coupling of β-Ketosulfoxides

Abstract

All Science Journal Classification (ASJC) codes

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