Criteria for the standardization of stem-cell-based embryo models

Alfonso Martinez Arias; Nicolas Rivron; Naomi Moris; Patrick Tam; Cantas Alev; Jianping Fu; Anna Katerina Hadjantonakis; Jacob H. Hanna; Gabriella Minchiotti; Olivier Pourquie; Guojun Sheng; Liliana Solnica Krezel; Jesse V. Veenvliet; Aryeh Warmflash

doi:10.1038/s41556-024-01492-x

Criteria for the standardization of stem-cell-based embryo models

Alfonso Martinez Arias, Nicolas Rivron, Naomi Moris, Patrick Tam, Cantas Alev, Jianping Fu, Anna Katerina Hadjantonakis, Jacob H. Hanna, Gabriella Minchiotti, Olivier Pourquie, Guojun Sheng, Liliana Solnica Krezel, Jesse V. Veenvliet, Aryeh Warmflash

Department of Molecular Genetics

Weizmann Institute of Science

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

Pluripotent stem cells are being used to generate models of early embryogenesis that are promising for discovery and translational research. To be useful, these models require critical consideration of their level of efficiency and fidelity to natural embryos. Here we propose criteria with which to raise the standards of stem-cell-based embryo models of human embryogenesis.

Original language	English
Pages (from-to)	1625-1628
Number of pages	4
Journal	Nature Cell Biology
Volume	26
Issue number	10
Early online date	2 Sep 2024
DOIs	https://doi.org/10.1038/s41556-024-01492-x
State	Published - Oct 2024

All Science Journal Classification (ASJC) codes

Cell Biology

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10.1038/s41556-024-01492-x

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title = "Criteria for the standardization of stem-cell-based embryo models",

abstract = "Pluripotent stem cells are being used to generate models of early embryogenesis that are promising for discovery and translational research. To be useful, these models require critical consideration of their level of efficiency and fidelity to natural embryos. Here we propose criteria with which to raise the standards of stem-cell-based embryo models of human embryogenesis.",

author = "\{Martinez Arias\}, Alfonso and Nicolas Rivron and Naomi Moris and Patrick Tam and Cantas Alev and Jianping Fu and Hadjantonakis, \{Anna Katerina\} and Hanna, \{Jacob H.\} and Gabriella Minchiotti and Olivier Pourquie and Guojun Sheng and \{Solnica Krezel\}, Liliana and Veenvliet, \{Jesse V.\} and Aryeh Warmflash",

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doi = "10.1038/s41556-024-01492-x",

language = "الإنجليزيّة",

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AU - Martinez Arias, Alfonso

AU - Rivron, Nicolas

AU - Moris, Naomi

AU - Tam, Patrick

AU - Alev, Cantas

AU - Fu, Jianping

AU - Hadjantonakis, Anna Katerina

AU - Hanna, Jacob H.

AU - Minchiotti, Gabriella

AU - Pourquie, Olivier

AU - Sheng, Guojun

AU - Solnica Krezel, Liliana

AU - Veenvliet, Jesse V.

AU - Warmflash, Aryeh

PY - 2024/10

Y1 - 2024/10

N2 - Pluripotent stem cells are being used to generate models of early embryogenesis that are promising for discovery and translational research. To be useful, these models require critical consideration of their level of efficiency and fidelity to natural embryos. Here we propose criteria with which to raise the standards of stem-cell-based embryo models of human embryogenesis.

AB - Pluripotent stem cells are being used to generate models of early embryogenesis that are promising for discovery and translational research. To be useful, these models require critical consideration of their level of efficiency and fidelity to natural embryos. Here we propose criteria with which to raise the standards of stem-cell-based embryo models of human embryogenesis.

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U2 - 10.1038/s41556-024-01492-x

DO - 10.1038/s41556-024-01492-x

M3 - تعليقَ / نقاش

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VL - 26

SP - 1625

EP - 1628

JO - Nature Cell Biology

JF - Nature Cell Biology

IS - 10

ER -

Criteria for the standardization of stem-cell-based embryo models

Abstract

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