Abstract
The discovery of clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR associated protein 9 (Cas9) system has emerged as a prominent system for genome engineering in diverse organisms. Biotechnological and industrial production of foods, beverages, chemicals, proteins and fuels is dependent on effective production systems, commonly utilizing the genetically modified organisms. CRISPR-Cas9 approach has been used for genome editing of wide range of fungi and yeast for industrial applications. It has enabled significant advances in mycology research by hastening the growth of study models for those aiming to discover and validate novel compounds. This chapter aims to bring a comprehensive detail on application of CRISPR-Cas9 mediated genome editing in different fungi toward industrial applications.
| Original language | American English |
|---|---|
| Title of host publication | Genome Engineering via CRISPR-Cas9 System |
| Publisher | Elsevier |
| Pages | 69-81 |
| Number of pages | 13 |
| ISBN (Electronic) | 9780128181409 |
| ISBN (Print) | 9780128181416 |
| DOIs | |
| State | Published - 1 Jan 2020 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 9 Industry, Innovation, and Infrastructure
Keywords
- CRISPR-Cas9
- Fungi
- Genetic innovations
- Genome editing
- Industrial applications
- sgRNA
All Science Journal Classification (ASJC) codes
- General Biochemistry,Genetics and Molecular Biology
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