Abstract
Background: The Dorsal transcription factor regulates the dorsal-ventral developmental gene regulatory network by binding to enhancers. Results: The core promoters of multiple Dorsal target genes are evolutionarily conserved and functionally dependent on specific elements. Conclusion: The core promoter composition is an important determinant of the transcriptional outcome. Significance: Transcriptional regulation results from an interplay between enhancers and core promoter composition.
| Original language | English |
|---|---|
| Pages (from-to) | 11993-12004 |
| Number of pages | 12 |
| Journal | Journal of Biological Chemistry |
| Volume | 289 |
| Issue number | 17 |
| DOIs | |
| State | Published - 25 Apr 2014 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Molecular Biology
- Cell Biology
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