Compositions and methods for prevention and treatment of neurodegenerative diseases

Ronit Ghaltiel-Karyo (Inventor), Ehud Gazit (Inventor)

Research output: Patent

Abstract

Isolated peptides are provided, being less than 20 amino acids in length. The peptides comprising an amino acid sequence GVLYVGSKTREGV (SEQ ID NO: 12) AAATGLVKREE (SEQ ID NO: 13) or GVVAAAEKTKQG (SEQ ID NO: 14), mimetics and/or fragment thereof, the peptides being capable of inhibiting alpha synuclein aggregation. Pharmaceutical compositions comprising same are also provided as well as uses thereof.

Original languageAmerican English
Patent numberCN102348720
IPCG01N 33/ 68 A I
Priority date9/03/10
StatePublished - 8 Feb 2012

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