TY - JOUR
T1 - Complexation of trace organic contaminants with fractionated dissolved organic matter
T2 - Implications for mass spectrometric quantification
AU - Ruiz, Selene Hernandez
AU - Wickramasekara, Samanthi
AU - Abrell, Leif
AU - Gao, Xiaodong
AU - Chefetz, Benny
AU - Chorover, Jon
N1 - Funding Information: Research support was provided by the Binational Agricultural Research and Development (BARD) fund, Grant # IS-3822-06 , the Water Research Foundation (Award #4269) and the University of Arizona Water Sustainability Program. The comments and views detailed herein may be necessarily reflecting the views of the Water Research Foundation, its officers, directors, affiliates, or agents. Analyses in the ALEC were supported by NSF Grant CBET-0722579.
PY - 2013/4
Y1 - 2013/4
N2 - Interaction with aqueous phase dissolved organic matter (DOM) can alter the fate of trace organic contaminants of emerging concern once they enter the water cycle. In order to probe possible DOM binding mechanisms and their consequences for contaminant detection and quantification in natural waters, a set of laboratory experiments was conducted with aqueous solutions containing various operationally-defined "hydrophilic" and "hydrophobic" freshwater DOM fractions isolated by resin adsorption techniques from reference Suwannee River natural organic matter (SROM). Per unit mass of SROM carbon, hydrophobic acids (HoA) comprised the largest C fraction (0.63±0.029), followed by hydrophilic-neutrals (HiN, 0.11±0.01) and acids (HiA, 0.09±0.017). Aqueous solutions comprising 8mgL-1 DOC of each SROM fraction were spiked with a concentration range (10-1000μgL-1) of bisphenol A (BPA), carbamazepine (CBZ), or ibuprofen (IBU) as model target compounds in 24mM NH4HCO3 background electrolyte at pH 7.4. Contaminant interaction with the SROM fractions was probed using fluorescence spectroscopy, and effects on quantitative analysis of the target compounds were measured using direct aqueous-injection liquid chromatography tandem mass spectrometry (LC-MS/MS). Total quenching was greater for the hydrophilic fractions of SROM and associations were principally with protein-like and fulvic acid-like constituents. Whereas LC-MS/MS recoveries indicated relatively weak interactions with most SROM factions, an important exception was the HiA fraction, which diminished recovery of CBZ and IBU by ca. 30% and 70%, respectively, indicating relatively strong molecular interactions.
AB - Interaction with aqueous phase dissolved organic matter (DOM) can alter the fate of trace organic contaminants of emerging concern once they enter the water cycle. In order to probe possible DOM binding mechanisms and their consequences for contaminant detection and quantification in natural waters, a set of laboratory experiments was conducted with aqueous solutions containing various operationally-defined "hydrophilic" and "hydrophobic" freshwater DOM fractions isolated by resin adsorption techniques from reference Suwannee River natural organic matter (SROM). Per unit mass of SROM carbon, hydrophobic acids (HoA) comprised the largest C fraction (0.63±0.029), followed by hydrophilic-neutrals (HiN, 0.11±0.01) and acids (HiA, 0.09±0.017). Aqueous solutions comprising 8mgL-1 DOC of each SROM fraction were spiked with a concentration range (10-1000μgL-1) of bisphenol A (BPA), carbamazepine (CBZ), or ibuprofen (IBU) as model target compounds in 24mM NH4HCO3 background electrolyte at pH 7.4. Contaminant interaction with the SROM fractions was probed using fluorescence spectroscopy, and effects on quantitative analysis of the target compounds were measured using direct aqueous-injection liquid chromatography tandem mass spectrometry (LC-MS/MS). Total quenching was greater for the hydrophilic fractions of SROM and associations were principally with protein-like and fulvic acid-like constituents. Whereas LC-MS/MS recoveries indicated relatively weak interactions with most SROM factions, an important exception was the HiA fraction, which diminished recovery of CBZ and IBU by ca. 30% and 70%, respectively, indicating relatively strong molecular interactions.
KW - EDC
KW - Fluorescence quenching
KW - LC-MS/MS
KW - PPCP
KW - Suwannee River natural organic matter
UR - http://www.scopus.com/inward/record.url?scp=84875052574&partnerID=8YFLogxK
U2 - https://doi.org/10.1016/j.chemosphere.2012.11.059
DO - https://doi.org/10.1016/j.chemosphere.2012.11.059
M3 - مقالة
C2 - 23276460
SN - 0045-6535
VL - 91
SP - 344
EP - 350
JO - Chemosphere
JF - Chemosphere
IS - 3
ER -