CombFold: predicting structures of large protein assemblies using a combinatorial assembly algorithm and AlphaFold2

Keyphrases

• Large Proteins 100%
• Protein Assembly 100%
• Combinatorial Assembly 100%
• AlphaFold 100%
• Structural Coverage 66%
• Top 10 33%
• Deep Learning Model 33%
• T-score 33%
• Protein Structure Prediction 33%
• Stoichiometry 33%
• Protein Data Bank 33%
• Oligomeric Proteins 33%
• Hierarchical Assembly 33%
• Pairwise Interaction 33%
• 20-High 33%
• Confidence Prediction 33%
• Bank Entry 33%
• Complex Stoichiometry 33%
• Cross-linking Mass Spectrometry 33%
• Asymmetric Assembly 33%
• RoseTTAFold 33%
• Complex Portal 33%
• Fast Enumeration 33%

Biochemistry, Genetics and Molecular Biology

• Protein Complexes 100%
• Stoichiometry 100%
• Protein Assembly 100%
• Mass Spectrometry 50%
• Protein Structure Prediction 50%
• Cross-Link 50%
• Protein Data Bank 50%