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Co-targeting of Adenosine Signaling Pathways for Immunotherapy: Potentiation by Fc Receptor Engagement

Rony Dahan, Jeffrey V. Ravetch

Research output: Contribution to journalShort surveypeer-review

Abstract

Targeting the signaling pathway of the immunosuppressive metabolite adenosine is an emerging approach for cancer immunotherapy. In this issue of Cancer Cell, Young et al. describe that co-inhibition of the adenosingenic pathway through blockade of both CD73 and A2AR enhances antitumor efficacy through distinct mechanisms.

Original languageEnglish
Pages (from-to)369-371
Number of pages3
JournalCancer Cell
Volume30
Issue number3
DOIs
StatePublished - 12 Sep 2016
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cell Biology
  • Cancer Research

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