@article{5c79ea0b2aa34deabd4766f378b753c4,
title = "Clonal Decomposition and DNA Replication States Defined by Scaled Single-Cell Genome Sequencing",
abstract = "A high-throughput method for amplication-free single-cell whole-genome sequencing can be scaled up to analyze tens of thousands of cells from different tissues and clinical sample types and identifies replication states, aneuploidies, and subclonal mutations.",
keywords = "DNA sequencing, aneuploidy, cancer genomics, cell cycle, copy number, genomic instability, single cell, tumor evolution, tumor heterogeneity",
author = "Emma Laks and Andrew McPherson and Hans Zahn and Daniel Lai and Adi Steif and Jazmine Brimhall and Justina Biele and Beixi Wang and Tehmina Masud and Jerome Ting and Diljot Grewal and Cydney Nielsen and Samantha Leung and Viktoria Bojilova and Maia Smith and Oleg Golovko and Steven Poon and Peter Eirew and Farhia Kabeer and {Ruiz de Algara}, Teresa and Lee, {So Ra} and Taghiyar, {M. Jafar} and Curtis Huebner and Jessica Ngo and Tim Chan and Spencer Vatrt-Watts and Pascale Walters and Nafis Abrar and Sophia Chan and Matt Wiens and Lauren Martin and Scott, {R. Wilder} and Underhill, {T. Michael} and Elizabeth Chavez and Christian Steidl and {Da Costa}, Daniel and Yussanne Ma and Coope, {Robin J.N.} and Richard Corbett and Stephen Pleasance and Richard Moore and Mungall, {Andrew J.} and Colin Mar and Fergus Cafferty and Karen Gelmon and Stephen Chia and Hannon, {Gregory J.} and Giorgia Battistoni and Dario Bressan and Shahar Alon",
note = "Publisher Copyright: {\textcopyright} 2019 The Authors",
year = "2019",
month = nov,
day = "14",
doi = "https://doi.org/10.1016/j.cell.2019.10.026",
language = "الإنجليزيّة",
volume = "179",
pages = "1207--1221.e22",
journal = "Cell",
issn = "0092-8674",
publisher = "Elsevier B.V.",
number = "5",
}