Chitosan-graft-poly(methyl methacrylate) amphiphilic nanoparticles: Self-association and physicochemical characterization: Self-association and physicochemical characterization

Inbar Schlachet; Jiri Trousil; Dmytro Rak; Kenneth D. Knudsen; Ewa Pavlova; Bo Nystrom; Alejandro Sosnik; Jiří Trousil; Bo Nyström

doi:https://doi.org/10.1016/j.carbpol.2019.02.022

Chitosan-graft-poly(methyl methacrylate) amphiphilic nanoparticles: Self-association and physicochemical characterization: Self-association and physicochemical characterization

Inbar Schlachet, Jiri Trousil, Dmytro Rak, Kenneth D. Knudsen, Ewa Pavlova, Bo Nystrom, Alejandro Sosnik, Jiří Trousil, Bo Nyström

Technion - Israel Institute of Technology

Research output: Contribution to journal › Article › peer-review

Abstract

In this work, we synthesized and characterized the self-assembly behavior of a chitosan-poly(methyl methacrylate) graft copolymer and the properties of the formed nanoparticles by static and dynamic light scattering, small-angle neutron scattering, and transmission electron microscopy. Overall, our results indicate that the hydrophobization of the chitosan side-chain with PMMA leads to a complex array of small unimolecular and/or small-aggregation number “building blocks” that further self-assemble into larger amphiphilic nanoparticles.

Original language	English
Pages (from-to)	412-420
Number of pages	9
Journal	Carbohydrate Polymers
Volume	212
DOIs	https://doi.org/10.1016/j.carbpol.2019.02.022
State	Published - 15 May 2019

Keywords

Amphiphilic polymeric nanoparticles
Chitosan-graft-poly(methyl methacrylate) copolymers
Self-assembly
Small-angle neutron scattering (SANS)
Static light scattering (SLS) and dynamic light scattering (DLS)

All Science Journal Classification (ASJC) codes

Organic Chemistry
Polymers and Plastics
Materials Chemistry

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https://doi.org/10.1016/j.carbpol.2019.02.022

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Schlachet, I., Trousil, J., Rak, D., Knudsen, K. D., Pavlova, E., Nystrom, B., Sosnik, A., Trousil, J., & Nyström, B. (2019). Chitosan-graft-poly(methyl methacrylate) amphiphilic nanoparticles: Self-association and physicochemical characterization: Self-association and physicochemical characterization. Carbohydrate Polymers, 212, 412-420. https://doi.org/10.1016/j.carbpol.2019.02.022

@article{494c9df23057415397d7bc17c10e1983,

title = "Chitosan-graft-poly(methyl methacrylate) amphiphilic nanoparticles: Self-association and physicochemical characterization: Self-association and physicochemical characterization",

abstract = "In this work, we synthesized and characterized the self-assembly behavior of a chitosan-poly(methyl methacrylate) graft copolymer and the properties of the formed nanoparticles by static and dynamic light scattering, small-angle neutron scattering, and transmission electron microscopy. Overall, our results indicate that the hydrophobization of the chitosan side-chain with PMMA leads to a complex array of small unimolecular and/or small-aggregation number “building blocks” that further self-assemble into larger amphiphilic nanoparticles.",

keywords = "Amphiphilic polymeric nanoparticles, Chitosan-graft-poly(methyl methacrylate) copolymers, Self-assembly, Small-angle neutron scattering (SANS), Static light scattering (SLS) and dynamic light scattering (DLS)",

author = "Inbar Schlachet and Jiri Trousil and Dmytro Rak and Knudsen, {Kenneth D.} and Ewa Pavlova and Bo Nystrom and Alejandro Sosnik and Ji{\v r}{\'i} Trousil and Bo Nystr{\"o}m",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Ltd",

year = "2019",

month = may,

day = "15",

doi = "https://doi.org/10.1016/j.carbpol.2019.02.022",

language = "الإنجليزيّة",

volume = "212",

pages = "412--420",

journal = "Carbohydrate Polymers",

issn = "0144-8617",

publisher = "Elsevier Ltd.",

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Schlachet, I, Trousil, J, Rak, D, Knudsen, KD, Pavlova, E, Nystrom, B, Sosnik, A, Trousil, J & Nyström, B 2019, 'Chitosan-graft-poly(methyl methacrylate) amphiphilic nanoparticles: Self-association and physicochemical characterization: Self-association and physicochemical characterization', Carbohydrate Polymers, vol. 212, pp. 412-420. https://doi.org/10.1016/j.carbpol.2019.02.022

TY - JOUR

T1 - Chitosan-graft-poly(methyl methacrylate) amphiphilic nanoparticles: Self-association and physicochemical characterization

T2 - Self-association and physicochemical characterization

AU - Schlachet, Inbar

AU - Trousil, Jiri

AU - Rak, Dmytro

AU - Knudsen, Kenneth D.

AU - Pavlova, Ewa

AU - Nystrom, Bo

AU - Sosnik, Alejandro

AU - Trousil, Jiří

AU - Nyström, Bo

PY - 2019/5/15

Y1 - 2019/5/15

N2 - In this work, we synthesized and characterized the self-assembly behavior of a chitosan-poly(methyl methacrylate) graft copolymer and the properties of the formed nanoparticles by static and dynamic light scattering, small-angle neutron scattering, and transmission electron microscopy. Overall, our results indicate that the hydrophobization of the chitosan side-chain with PMMA leads to a complex array of small unimolecular and/or small-aggregation number “building blocks” that further self-assemble into larger amphiphilic nanoparticles.

AB - In this work, we synthesized and characterized the self-assembly behavior of a chitosan-poly(methyl methacrylate) graft copolymer and the properties of the formed nanoparticles by static and dynamic light scattering, small-angle neutron scattering, and transmission electron microscopy. Overall, our results indicate that the hydrophobization of the chitosan side-chain with PMMA leads to a complex array of small unimolecular and/or small-aggregation number “building blocks” that further self-assemble into larger amphiphilic nanoparticles.

KW - Amphiphilic polymeric nanoparticles

KW - Chitosan-graft-poly(methyl methacrylate) copolymers

KW - Self-assembly

KW - Small-angle neutron scattering (SANS)

KW - Static light scattering (SLS) and dynamic light scattering (DLS)

UR - http://www.scopus.com/inward/record.url?scp=85062021838&partnerID=8YFLogxK

U2 - https://doi.org/10.1016/j.carbpol.2019.02.022

DO - https://doi.org/10.1016/j.carbpol.2019.02.022

M3 - مقالة

SN - 0144-8617

VL - 212

SP - 412

EP - 420

JO - Carbohydrate Polymers

JF - Carbohydrate Polymers

ER -

Chitosan-graft-poly(methyl methacrylate) amphiphilic nanoparticles: Self-association and physicochemical characterization: Self-association and physicochemical characterization

Abstract

Keywords

All Science Journal Classification (ASJC) codes

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