Chemical Synthesis of Selenoproteins

Rebecca N. Dardashti; Reem Ghadir; Hiba Ghareeb; Orit Weil-Ktorza; Norman Metanis

doi:10.1002/9783527823567.ch17

Chemical Synthesis of Selenoproteins

Rebecca N. Dardashti, Reem Ghadir, Hiba Ghareeb, Orit Weil-Ktorza, Norman Metanis

Institute of Chemistry

The Hebrew University of Jerusalem

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Chemical protein synthesis is a great approach for accessing challenging proteins, such as post-translationally modified proteins, proteins with unnatural amino acids, and proteins with rare natural amino acids such as selenoproteins. In this book chapter we will discuss the recent advances in the chemical synthesis of selenoproteins, as well as the unique chemistry of selenopeptides and selenoproteins.

Original language	English
Title of host publication	Total Chemical Synthesis of Proteins
Pages	463-488
Number of pages	26
ISBN (Electronic)	9783527823567
DOIs	https://doi.org/10.1002/9783527823567.ch17
State	Published - 1 Jan 2021

Keywords

Selenocysteine
chemical protein synthesis
chemoselective reactions
native chemical ligation
selenopeptides
selenoproteins

All Science Journal Classification (ASJC) codes

General Chemistry

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10.1002/9783527823567.ch17

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AU - Weil-Ktorza, Orit

AU - Metanis, Norman

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KW - chemical protein synthesis

KW - chemoselective reactions

KW - native chemical ligation

KW - selenopeptides

KW - selenoproteins

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Chemical Synthesis of Selenoproteins

Abstract

Keywords

All Science Journal Classification (ASJC) codes

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