CHEMICAL PREPARATION OF POLYUBIQUITIN CHAINS

Ashraf Brik; Mahmood Haj-Yahya; Ajish Kumar; Leslie Erlich; Liat Spasser

CHEMICAL PREPARATION OF POLYUBIQUITIN CHAINS

Ashraf Brik (Inventor), Mahmood Haj-Yahya (Inventor), Ajish Kumar (Inventor), Leslie Erlich (Inventor), Liat Spasser (Inventor)

Chemistry

Technion - Israel Institute of Technology

Research output: Patent

Abstract

The present invention discloses a process for the preparation of a Poly-ubiquitin chain, this process comprising ligating a Ubiquitin thioester Ubm-SR with a Ubiquitin Ubq. Further are disclosed poly-ubiquitin chains prepared according to this process, in particular poly-ubiquitin chains containing at least one unnatural amino acid.

Original language	American English
Patent number	US2013060003
IPC	C07K 14/ 00 A I
Priority date	9/02/11
State	Published - 7 Mar 2013

Cite this

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title = "CHEMICAL PREPARATION OF POLYUBIQUITIN CHAINS",

abstract = "The present invention discloses a process for the preparation of a Poly-ubiquitin chain, this process comprising ligating a Ubiquitin thioester Ubm-SR with a Ubiquitin Ubq. Further are disclosed poly-ubiquitin chains prepared according to this process, in particular poly-ubiquitin chains containing at least one unnatural amino acid.",

author = "Ashraf Brik and Mahmood Haj-Yahya and Ajish Kumar and Leslie Erlich and Liat Spasser",

year = "2013",

month = mar,

day = "7",

language = "American English",

type = "Patent",

note = "US2013060003; C07K 14/ 00 A I",

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TY - PAT

T1 - CHEMICAL PREPARATION OF POLYUBIQUITIN CHAINS

AU - Brik, Ashraf

AU - Haj-Yahya, Mahmood

AU - Kumar, Ajish

AU - Erlich, Leslie

AU - Spasser, Liat

PY - 2013/3/7

Y1 - 2013/3/7

N2 - The present invention discloses a process for the preparation of a Poly-ubiquitin chain, this process comprising ligating a Ubiquitin thioester Ubm-SR with a Ubiquitin Ubq. Further are disclosed poly-ubiquitin chains prepared according to this process, in particular poly-ubiquitin chains containing at least one unnatural amino acid.

AB - The present invention discloses a process for the preparation of a Poly-ubiquitin chain, this process comprising ligating a Ubiquitin thioester Ubm-SR with a Ubiquitin Ubq. Further are disclosed poly-ubiquitin chains prepared according to this process, in particular poly-ubiquitin chains containing at least one unnatural amino acid.

M3 - Patent

M1 - US2013060003

ER -

CHEMICAL PREPARATION OF POLYUBIQUITIN CHAINS

Abstract

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