Characteristics of endovascular pneumococcal infections; a decade of nationwide surveillance study

Ariel Kenig; Yonatan Oster; Ronit Cohen-Poradosu; Klaris Reisenberg; Anat Wieder-Finesod; Mirit Hershman-Sarafov; Ilana Oren; Gabriel Weber; Ron Dagan; Gili Regev-Yochay; Jacob Strahilevitz

doi:10.1007/s10096-022-04500-w

Characteristics of endovascular pneumococcal infections; a decade of nationwide surveillance study

Ariel Kenig, Yonatan Oster, Ronit Cohen-Poradosu, Klaris Reisenberg, Anat Wieder-Finesod, Mirit Hershman-Sarafov, Ilana Oren, Gabriel Weber, Ron Dagan, Gili Regev-Yochay, Jacob Strahilevitz

The Hebrew University of Jerusalem, Ben-Gurion University of the Negev, Technion - Israel Institute of Technology, Tel Aviv University

Research output: Contribution to journal › Article › peer-review

Abstract

In order to characterize pneumococcal endovascular infection in the post-vaccination era, a retrospective nationwide study based on the Israeli Adult IPD database was conducted. Between 2010 and 2019, 0.6% (23 cases) of IPD cases were of endovascular type, occurring mainly in males (72.3%) with underlying medical conditions (78.2%). Additional pneumococcal source (10 patients) and concomitant infections were not uncommon. Penicillin and ceftriaxone susceptibility rates were 65.2% and 91.3%, respectively; 60.9% of the isolates were not covered by the pneumococcal conjugate vaccine. 21.7% of patients died during hospitalization. In conclusion, pneumococcal endovascular infections still carry significant morbidity and mortality.

Original language	English
Pages (from-to)	1365-1370
Number of pages	6
Journal	European Journal of Clinical Microbiology and Infectious Diseases
Volume	41
Issue number	11
DOIs	https://doi.org/10.1007/s10096-022-04500-w
State	Published - 1 Nov 2022

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Endovascular infections
Infective endocarditis
Invasive pneumococcal disease
Streptococcuspneumoniae

All Science Journal Classification (ASJC) codes

Microbiology (medical)
Infectious Diseases

Access to Document

10.1007/s10096-022-04500-w

Cite this

Kenig, A., Oster, Y., Cohen-Poradosu, R., Reisenberg, K., Wieder-Finesod, A., Hershman-Sarafov, M., Oren, I., Weber, G., Dagan, R., Regev-Yochay, G., & Strahilevitz, J. (2022). Characteristics of endovascular pneumococcal infections; a decade of nationwide surveillance study. European Journal of Clinical Microbiology and Infectious Diseases, 41(11), 1365-1370. https://doi.org/10.1007/s10096-022-04500-w

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title = "Characteristics of endovascular pneumococcal infections; a decade of nationwide surveillance study",

abstract = "In order to characterize pneumococcal endovascular infection in the post-vaccination era, a retrospective nationwide study based on the Israeli Adult IPD database was conducted. Between 2010 and 2019, 0.6\% (23 cases) of IPD cases were of endovascular type, occurring mainly in males (72.3\%) with underlying medical conditions (78.2\%). Additional pneumococcal source (10 patients) and concomitant infections were not uncommon. Penicillin and ceftriaxone susceptibility rates were 65.2\% and 91.3\%, respectively; 60.9\% of the isolates were not covered by the pneumococcal conjugate vaccine. 21.7\% of patients died during hospitalization. In conclusion, pneumococcal endovascular infections still carry significant morbidity and mortality.",

keywords = "Endovascular infections, Infective endocarditis, Invasive pneumococcal disease, Streptococcuspneumoniae",

author = "Ariel Kenig and Yonatan Oster and Ronit Cohen-Poradosu and Klaris Reisenberg and Anat Wieder-Finesod and Mirit Hershman-Sarafov and Ilana Oren and Gabriel Weber and Ron Dagan and Gili Regev-Yochay and Jacob Strahilevitz",

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year = "2022",

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doi = "10.1007/s10096-022-04500-w",

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Kenig, A, Oster, Y, Cohen-Poradosu, R, Reisenberg, K, Wieder-Finesod, A, Hershman-Sarafov, M, Oren, I, Weber, G, Dagan, R, Regev-Yochay, G & Strahilevitz, J 2022, 'Characteristics of endovascular pneumococcal infections; a decade of nationwide surveillance study', European Journal of Clinical Microbiology and Infectious Diseases, vol. 41, no. 11, pp. 1365-1370. https://doi.org/10.1007/s10096-022-04500-w

TY - JOUR

T1 - Characteristics of endovascular pneumococcal infections; a decade of nationwide surveillance study

AU - Kenig, Ariel

AU - Oster, Yonatan

AU - Cohen-Poradosu, Ronit

AU - Reisenberg, Klaris

AU - Wieder-Finesod, Anat

AU - Hershman-Sarafov, Mirit

AU - Oren, Ilana

AU - Weber, Gabriel

AU - Dagan, Ron

AU - Regev-Yochay, Gili

AU - Strahilevitz, Jacob

PY - 2022/11/1

Y1 - 2022/11/1

N2 - In order to characterize pneumococcal endovascular infection in the post-vaccination era, a retrospective nationwide study based on the Israeli Adult IPD database was conducted. Between 2010 and 2019, 0.6% (23 cases) of IPD cases were of endovascular type, occurring mainly in males (72.3%) with underlying medical conditions (78.2%). Additional pneumococcal source (10 patients) and concomitant infections were not uncommon. Penicillin and ceftriaxone susceptibility rates were 65.2% and 91.3%, respectively; 60.9% of the isolates were not covered by the pneumococcal conjugate vaccine. 21.7% of patients died during hospitalization. In conclusion, pneumococcal endovascular infections still carry significant morbidity and mortality.

AB - In order to characterize pneumococcal endovascular infection in the post-vaccination era, a retrospective nationwide study based on the Israeli Adult IPD database was conducted. Between 2010 and 2019, 0.6% (23 cases) of IPD cases were of endovascular type, occurring mainly in males (72.3%) with underlying medical conditions (78.2%). Additional pneumococcal source (10 patients) and concomitant infections were not uncommon. Penicillin and ceftriaxone susceptibility rates were 65.2% and 91.3%, respectively; 60.9% of the isolates were not covered by the pneumococcal conjugate vaccine. 21.7% of patients died during hospitalization. In conclusion, pneumococcal endovascular infections still carry significant morbidity and mortality.

KW - Endovascular infections

KW - Infective endocarditis

KW - Invasive pneumococcal disease

KW - Streptococcuspneumoniae

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U2 - 10.1007/s10096-022-04500-w

DO - 10.1007/s10096-022-04500-w

M3 - مقالة

C2 - 36175812

SN - 0934-9723

VL - 41

SP - 1365

EP - 1370

JO - European Journal of Clinical Microbiology and Infectious Diseases

JF - European Journal of Clinical Microbiology and Infectious Diseases

IS - 11

ER -

Characteristics of endovascular pneumococcal infections; a decade of nationwide surveillance study

Abstract

UN SDGs

Keywords

All Science Journal Classification (ASJC) codes

Access to Document

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