Characteristics of endovascular pneumococcal infections; a decade of nationwide surveillance study

Ariel Kenig; Yonatan Oster; Ronit Cohen-Poradosu; Klaris Reisenberg; Anat Wieder-Finesod; Mirit Hershman-Sarafov; Ilana Oren; Gabriel Weber; Ron Dagan; Gili Regev-Yochay; Jacob Strahilevitz

doi:10.1007/s10096-022-04500-w

Characteristics of endovascular pneumococcal infections; a decade of nationwide surveillance study

Ariel Kenig, Yonatan Oster, Ronit Cohen-Poradosu, Klaris Reisenberg, Anat Wieder-Finesod, Mirit Hershman-Sarafov, Ilana Oren, Gabriel Weber, Ron Dagan, Gili Regev-Yochay, Jacob Strahilevitz

The Hebrew University of Jerusalem, Ben-Gurion University of the Negev, Technion - Israel Institute of Technology, Tel Aviv University

Research output: Contribution to journal › Article › peer-review

Abstract

In order to characterize pneumococcal endovascular infection in the post-vaccination era, a retrospective nationwide study based on the Israeli Adult IPD database was conducted. Between 2010 and 2019, 0.6% (23 cases) of IPD cases were of endovascular type, occurring mainly in males (72.3%) with underlying medical conditions (78.2%). Additional pneumococcal source (10 patients) and concomitant infections were not uncommon. Penicillin and ceftriaxone susceptibility rates were 65.2% and 91.3%, respectively; 60.9% of the isolates were not covered by the pneumococcal conjugate vaccine. 21.7% of patients died during hospitalization. In conclusion, pneumococcal endovascular infections still carry significant morbidity and mortality.

Original language	English
Pages (from-to)	1365-1370
Number of pages	6
Journal	European Journal of Clinical Microbiology and Infectious Diseases
Volume	41
Issue number	11
DOIs	https://doi.org/10.1007/s10096-022-04500-w
State	Published - 1 Nov 2022

Keywords

Endovascular infections
Infective endocarditis
Invasive pneumococcal disease
Streptococcuspneumoniae

All Science Journal Classification (ASJC) codes

Microbiology (medical)
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s10096-022-04500-w

Cite this

Kenig, A., Oster, Y., Cohen-Poradosu, R., Reisenberg, K., Wieder-Finesod, A., Hershman-Sarafov, M., Oren, I., Weber, G., Dagan, R., Regev-Yochay, G., & Strahilevitz, J. (2022). Characteristics of endovascular pneumococcal infections; a decade of nationwide surveillance study. European Journal of Clinical Microbiology and Infectious Diseases, 41(11), 1365-1370. https://doi.org/10.1007/s10096-022-04500-w

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title = "Characteristics of endovascular pneumococcal infections; a decade of nationwide surveillance study",

abstract = "In order to characterize pneumococcal endovascular infection in the post-vaccination era, a retrospective nationwide study based on the Israeli Adult IPD database was conducted. Between 2010 and 2019, 0.6% (23 cases) of IPD cases were of endovascular type, occurring mainly in males (72.3%) with underlying medical conditions (78.2%). Additional pneumococcal source (10 patients) and concomitant infections were not uncommon. Penicillin and ceftriaxone susceptibility rates were 65.2% and 91.3%, respectively; 60.9% of the isolates were not covered by the pneumococcal conjugate vaccine. 21.7% of patients died during hospitalization. In conclusion, pneumococcal endovascular infections still carry significant morbidity and mortality.",

keywords = "Endovascular infections, Infective endocarditis, Invasive pneumococcal disease, Streptococcuspneumoniae",

author = "Ariel Kenig and Yonatan Oster and Ronit Cohen-Poradosu and Klaris Reisenberg and Anat Wieder-Finesod and Mirit Hershman-Sarafov and Ilana Oren and Gabriel Weber and Ron Dagan and Gili Regev-Yochay and Jacob Strahilevitz",

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doi = "10.1007/s10096-022-04500-w",

language = "الإنجليزيّة",

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Kenig, A, Oster, Y, Cohen-Poradosu, R, Reisenberg, K, Wieder-Finesod, A, Hershman-Sarafov, M, Oren, I, Weber, G, Dagan, R, Regev-Yochay, G & Strahilevitz, J 2022, 'Characteristics of endovascular pneumococcal infections; a decade of nationwide surveillance study', European Journal of Clinical Microbiology and Infectious Diseases, vol. 41, no. 11, pp. 1365-1370. https://doi.org/10.1007/s10096-022-04500-w

TY - JOUR

T1 - Characteristics of endovascular pneumococcal infections; a decade of nationwide surveillance study

AU - Kenig, Ariel

AU - Oster, Yonatan

AU - Cohen-Poradosu, Ronit

AU - Reisenberg, Klaris

AU - Wieder-Finesod, Anat

AU - Hershman-Sarafov, Mirit

AU - Oren, Ilana

AU - Weber, Gabriel

AU - Dagan, Ron

AU - Regev-Yochay, Gili

AU - Strahilevitz, Jacob

PY - 2022/11/1

Y1 - 2022/11/1

N2 - In order to characterize pneumococcal endovascular infection in the post-vaccination era, a retrospective nationwide study based on the Israeli Adult IPD database was conducted. Between 2010 and 2019, 0.6% (23 cases) of IPD cases were of endovascular type, occurring mainly in males (72.3%) with underlying medical conditions (78.2%). Additional pneumococcal source (10 patients) and concomitant infections were not uncommon. Penicillin and ceftriaxone susceptibility rates were 65.2% and 91.3%, respectively; 60.9% of the isolates were not covered by the pneumococcal conjugate vaccine. 21.7% of patients died during hospitalization. In conclusion, pneumococcal endovascular infections still carry significant morbidity and mortality.

AB - In order to characterize pneumococcal endovascular infection in the post-vaccination era, a retrospective nationwide study based on the Israeli Adult IPD database was conducted. Between 2010 and 2019, 0.6% (23 cases) of IPD cases were of endovascular type, occurring mainly in males (72.3%) with underlying medical conditions (78.2%). Additional pneumococcal source (10 patients) and concomitant infections were not uncommon. Penicillin and ceftriaxone susceptibility rates were 65.2% and 91.3%, respectively; 60.9% of the isolates were not covered by the pneumococcal conjugate vaccine. 21.7% of patients died during hospitalization. In conclusion, pneumococcal endovascular infections still carry significant morbidity and mortality.

KW - Endovascular infections

KW - Infective endocarditis

KW - Invasive pneumococcal disease

KW - Streptococcuspneumoniae

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U2 - 10.1007/s10096-022-04500-w

DO - 10.1007/s10096-022-04500-w

M3 - مقالة

C2 - 36175812

SN - 0934-9723

VL - 41

SP - 1365

EP - 1370

JO - European Journal of Clinical Microbiology and Infectious Diseases

JF - European Journal of Clinical Microbiology and Infectious Diseases

IS - 11

ER -

Characteristics of endovascular pneumococcal infections; a decade of nationwide surveillance study

Abstract

Keywords

All Science Journal Classification (ASJC) codes

UN SDGs

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