Chaperones: Speedy motion for function

Hagen Hofmann

doi:10.1038/nchembio.2130

Chaperones: Speedy motion for function

Hagen Hofmann

Department of Chemical and Structural Biology

Weizmann Institute of Science

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

Hsp90 is an energy-consuming molecular chaperone that activates oncogenic proteins in a complicated multi-step reaction. Photoinduced electron transfer (PET) quenching experiments with a fluorescent reporter have now identified molecular transitions at multiple timescales in the chaperone cycle of Hsp90.

Original language	English
Pages (from-to)	576-577
Number of pages	2
Journal	Nature Chemical Biology
Volume	12
Issue number	8
DOIs	https://doi.org/10.1038/nchembio.2130
State	Published - 19 Jul 2016

All Science Journal Classification (ASJC) codes

Molecular Biology
Cell Biology

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10.1038/nchembio.2130

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abstract = "Hsp90 is an energy-consuming molecular chaperone that activates oncogenic proteins in a complicated multi-step reaction. Photoinduced electron transfer (PET) quenching experiments with a fluorescent reporter have now identified molecular transitions at multiple timescales in the chaperone cycle of Hsp90.",

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Chaperones: Speedy motion for function

Abstract

All Science Journal Classification (ASJC) codes

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