Challenges for precision public health communication in the era of genomic medicine

Aviad Raz, Stefan Timmermans, Gil Eyal, Kyle Brothers, Jusaku Minari

Research output: Contribution to journalArticlepeer-review


Although still in the early stages of development, the advent of fast, high-output, and cost-effective next-generation DNA sequencing technology is moving precision medicine into public health. Before this shift toward next-generation sequencing in public health settings, individual patients met geneticists after showing symptoms and through limited family screening. In the new era of precision public health, everyone is a possible participant in genetic sequencing, simply by being born (newborn screening), by donating blood (biobanking), or through population screening. These initiatives are increasingly offered to individuals throughout their life and more individuals are encountering opportunities to use DNA sequencing. This article raises awareness of these growing areas and calls for different models of public engagement and communication about genomics, including screening asymptomatic populations, obtaining consent for unspecified and unforeseen future uses of genomic data, and managing variants of uncertain significance. Given that such communication challenges loom large, established norms of practice in genomic medicine and research should be reconsidered.

Original languageEnglish
Pages (from-to)1814-1820
Number of pages7
JournalGenetics in Medicine
Issue number9
StatePublished - 1 Sep 2022


  • Biobanking
  • Communication
  • New generation sequencing
  • Newborn screening
  • Precision medicine

All Science Journal Classification (ASJC) codes

  • Genetics(clinical)


Dive into the research topics of 'Challenges for precision public health communication in the era of genomic medicine'. Together they form a unique fingerprint.

Cite this