Cell-Type-Specific Outcome Representation in the Primary Motor Cortex

Shahar Levy; Maria Lavzin; Hadas Benisty; Amir Ghanayim; Uri Dubin; Shay Achvat; Zohar Brosh; Fadi Aeed; Brett D. Mensh; Schiller Yitzhak; Ron Meir; Omri Barak; Ronen Talmon; Adam W. Hantman; Jackie Schiller

doi:10.1016/j.neuron.2020.06.006

Cell-Type-Specific Outcome Representation in the Primary Motor Cortex

Shahar Levy, Maria Lavzin, Hadas Benisty, Amir Ghanayim, Uri Dubin, Shay Achvat, Zohar Brosh, Fadi Aeed, Brett D. Mensh, Schiller Yitzhak, Ron Meir, Omri Barak, Ronen Talmon, Adam W. Hantman, Jackie Schiller

Technion - Israel Institute of Technology

Research output: Contribution to journal › Article › peer-review

Abstract

Monitoring outcome is critical for acquiring skilled movements. Levy et al. describe activity in subpopulations of layer 2–3 motor cortex pyramidal neurons that distinctly report outcomes of previous successes and failures independent of kinematics and reward. These signals may serve as reinforcement learning processes involved in maintaining or learning skilled movements.

Original language	English
Pages (from-to)	954-971.e9
Journal	Neuron
Volume	107
Issue number	5
DOIs	https://doi.org/10.1016/j.neuron.2020.06.006
State	Published - 9 Sep 2020

Keywords

layer 2-3
layer 5
motor cortex
motor learning
outcome
pyramidal tract neurons
reward
two-photon calcium imaging

All Science Journal Classification (ASJC) codes

General Neuroscience

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10.1016/j.neuron.2020.06.006

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title = "Cell-Type-Specific Outcome Representation in the Primary Motor Cortex",

abstract = "Monitoring outcome is critical for acquiring skilled movements. Levy et al. describe activity in subpopulations of layer 2–3 motor cortex pyramidal neurons that distinctly report outcomes of previous successes and failures independent of kinematics and reward. These signals may serve as reinforcement learning processes involved in maintaining or learning skilled movements.",

keywords = "layer 2-3, layer 5, motor cortex, motor learning, outcome, pyramidal tract neurons, reward, two-photon calcium imaging",

author = "Shahar Levy and Maria Lavzin and Hadas Benisty and Amir Ghanayim and Uri Dubin and Shay Achvat and Zohar Brosh and Fadi Aeed and Mensh, \{Brett D.\} and Schiller Yitzhak and Ron Meir and Omri Barak and Ronen Talmon and Hantman, \{Adam W.\} and Jackie Schiller",

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year = "2020",

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doi = "10.1016/j.neuron.2020.06.006",

language = "الإنجليزيّة",

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T1 - Cell-Type-Specific Outcome Representation in the Primary Motor Cortex

AU - Levy, Shahar

AU - Lavzin, Maria

AU - Benisty, Hadas

AU - Ghanayim, Amir

AU - Dubin, Uri

AU - Achvat, Shay

AU - Brosh, Zohar

AU - Aeed, Fadi

AU - Mensh, Brett D.

AU - Yitzhak, Schiller

AU - Meir, Ron

AU - Barak, Omri

AU - Talmon, Ronen

AU - Hantman, Adam W.

AU - Schiller, Jackie

PY - 2020/9/9

Y1 - 2020/9/9

N2 - Monitoring outcome is critical for acquiring skilled movements. Levy et al. describe activity in subpopulations of layer 2–3 motor cortex pyramidal neurons that distinctly report outcomes of previous successes and failures independent of kinematics and reward. These signals may serve as reinforcement learning processes involved in maintaining or learning skilled movements.

AB - Monitoring outcome is critical for acquiring skilled movements. Levy et al. describe activity in subpopulations of layer 2–3 motor cortex pyramidal neurons that distinctly report outcomes of previous successes and failures independent of kinematics and reward. These signals may serve as reinforcement learning processes involved in maintaining or learning skilled movements.

KW - layer 2-3

KW - layer 5

KW - motor cortex

KW - motor learning

KW - outcome

KW - pyramidal tract neurons

KW - reward

KW - two-photon calcium imaging

UR - http://www.scopus.com/inward/record.url?scp=85087691802&partnerID=8YFLogxK

U2 - 10.1016/j.neuron.2020.06.006

DO - 10.1016/j.neuron.2020.06.006

M3 - مقالة

SN - 0896-6273

VL - 107

SP - 954-971.e9

JO - Neuron

JF - Neuron

IS - 5

ER -

Cell-Type-Specific Outcome Representation in the Primary Motor Cortex

Abstract

Keywords

All Science Journal Classification (ASJC) codes

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