TY - JOUR
T1 - Cell polarity signaling
AU - Bloch, Daria
AU - Yalovsky, Shaul
N1 - Funding Information: Research in the Yalovsky laboratory is supported by Israel Science Foundation ( ISF 1244/11 ), US-Israel Binational Science Foundation ( BSF 2009309 ), Israel Center Of Research Excellence ( I-CORE 757/12 ), the ISF-NCSF ( ISF-China 1125/13 ) and The Manna Center for Plant Sciences at Tel Aviv University
PY - 2013
Y1 - 2013
N2 - Cell polarity is a fundamental entity of living organisms. Cells must receive accurate decisions where to divide and along which plane, along which axis to grow, where to grow structures like flagellum or filopodium and how to differentially respond to external stimuli. In multicellular organisms cell polarity also regulates cell-cell communication, pattern formation and cell identity. In eukaryotes the RHO family of small G proteins have emerged as central regulators of cell polarity signaling. It is by now well established that ROPs, the plant specific RHO subfamily members, affect cell polarization. Work carried out over the last several years is beginning to reveal how ROPs are activated, how their activity is spatially regulated, through which effectors they regulate cell polarity and how they interact with hormonal signaling and other polarity determinants. The emerging picture is that while the mechanisms of cell polarity signaling are often unique to plants, the principles that govern cell polarization signaling can be similar. In this review, we provide an updated view of polarity signaling in plants, primarily focusing on the function of ROPs and how they interact with and coordinate different polarity determinants.
AB - Cell polarity is a fundamental entity of living organisms. Cells must receive accurate decisions where to divide and along which plane, along which axis to grow, where to grow structures like flagellum or filopodium and how to differentially respond to external stimuli. In multicellular organisms cell polarity also regulates cell-cell communication, pattern formation and cell identity. In eukaryotes the RHO family of small G proteins have emerged as central regulators of cell polarity signaling. It is by now well established that ROPs, the plant specific RHO subfamily members, affect cell polarization. Work carried out over the last several years is beginning to reveal how ROPs are activated, how their activity is spatially regulated, through which effectors they regulate cell polarity and how they interact with hormonal signaling and other polarity determinants. The emerging picture is that while the mechanisms of cell polarity signaling are often unique to plants, the principles that govern cell polarization signaling can be similar. In this review, we provide an updated view of polarity signaling in plants, primarily focusing on the function of ROPs and how they interact with and coordinate different polarity determinants.
UR - http://www.scopus.com/inward/record.url?scp=84888429017&partnerID=8YFLogxK
U2 - https://doi.org/10.1016/j.pbi.2013.10.009
DO - https://doi.org/10.1016/j.pbi.2013.10.009
M3 - مقالة مرجعية
SN - 1369-5266
VL - 16
SP - 734
EP - 742
JO - Current Opinion in Plant Biology
JF - Current Opinion in Plant Biology
IS - 6
ER -