Carriage of Colibactin-producing Bacteria and Colorectal Cancer Risk

Vadim Dubinsky; Iris Dotan; Uri Gophna

doi:https://doi.org/10.1016/j.tim.2020.05.015

Carriage of Colibactin-producing Bacteria and Colorectal Cancer Risk

Vadim Dubinsky, Iris Dotan, Uri Gophna

Tel Aviv University

Research output: Contribution to journal › Short survey › peer-review

Abstract

Colibactin is a genotoxic molecule, produced primarily by Escherichia coli. Colibactin causes DNA damage that may lead to colorectal cancer. Here we review recent advances in the study of colibactin and propose a focus on patients with inflammatory bowel diseases (IBD) who have higher levels of colibactin-producing bacteria in their intestines.

Original language	English
Pages (from-to)	874-876
Number of pages	3
Journal	Trends in Microbiology
Volume	28
Issue number	11
DOIs	https://doi.org/10.1016/j.tim.2020.05.015
State	Published - Nov 2020

All Science Journal Classification (ASJC) codes

Microbiology
Microbiology (medical)
Virology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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https://doi.org/10.1016/j.tim.2020.05.015

Cite this

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title = "Carriage of Colibactin-producing Bacteria and Colorectal Cancer Risk",

abstract = "Colibactin is a genotoxic molecule, produced primarily by Escherichia coli. Colibactin causes DNA damage that may lead to colorectal cancer. Here we review recent advances in the study of colibactin and propose a focus on patients with inflammatory bowel diseases (IBD) who have higher levels of colibactin-producing bacteria in their intestines.",

author = "Vadim Dubinsky and Iris Dotan and Uri Gophna",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Ltd",

year = "2020",

month = nov,

doi = "https://doi.org/10.1016/j.tim.2020.05.015",

language = "الإنجليزيّة",

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journal = "Trends in Microbiology",

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AU - Dubinsky, Vadim

AU - Dotan, Iris

AU - Gophna, Uri

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N2 - Colibactin is a genotoxic molecule, produced primarily by Escherichia coli. Colibactin causes DNA damage that may lead to colorectal cancer. Here we review recent advances in the study of colibactin and propose a focus on patients with inflammatory bowel diseases (IBD) who have higher levels of colibactin-producing bacteria in their intestines.

AB - Colibactin is a genotoxic molecule, produced primarily by Escherichia coli. Colibactin causes DNA damage that may lead to colorectal cancer. Here we review recent advances in the study of colibactin and propose a focus on patients with inflammatory bowel diseases (IBD) who have higher levels of colibactin-producing bacteria in their intestines.

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U2 - https://doi.org/10.1016/j.tim.2020.05.015

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M3 - عرض مختصر

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JO - Trends in Microbiology

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IS - 11

ER -

Carriage of Colibactin-producing Bacteria and Colorectal Cancer Risk

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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