Cardiac Tissue Engineering: Principles, Materials, and Applications

Emil Ruvinov, Yulia Sapir, Smadar Cohen

Research output: Book/ReportBookpeer-review


Cardiac tissue engineering aims at repairing damaged heart muscle and producing human cardiac tissues for application in drug toxicity studies. This book offers a comprehensive overview of the cardiac tissue engineering strategies, including presenting and discussing the various concepts in use, research directions and applications. Essential basic information on the major components in cardiac tissue engineering, namely cell sources and biomaterials, is firstly presented to the readers, followed by a detailed description of their implementation in different strategies, broadly divided to cellular and acellular ones. In cellular approaches, the biomaterials are used to increase cell retention after implantation or as scaffolds when bioengineering the cardiac patch, in vitro. In acellular approaches, the biomaterials are used as ECM replacement for damaged cardiac ECM after MI, or, in combination with growth factors, the biomaterials assume an additional function as a depot for prolonged factor ac...
Original languageAmerican English
PublisherSpringer Nature Switzerland AG
Number of pages190
ISBN (Electronic)978-3-031-02584-6
ISBN (Print)978-3-031-01456-7
StatePublished - 29 Sep 2011

Publication series

NameSynthesis Lectures on Tissue Engineering


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