Capturing the diversity of protein modifications on presented tumor antigens

Aaron Javitt; Yifat Merbl

doi:10.1038/s41587-022-01465-1

Capturing the diversity of protein modifications on presented tumor antigens

Aaron Javitt, Yifat Merbl

Department of Systems Immunology

Weizmann Institute of Science

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

Post-translational modifications (PTMs) alter the structure, properties and functions of proteins in all aspects of biology. A new computational pipeline, termed protein modification integrated search engine (PROMISE), reveals the impact these modifications might have on the presentation of cancer antigens to T cells.

Original language	English
Pages (from-to)	195-196
Number of pages	2
Journal	Nature biotechnology
Volume	41
Issue number	2
Early online date	10 Oct 2022
DOIs	https://doi.org/10.1038/s41587-022-01465-1
State	Published - Feb 2023

All Science Journal Classification (ASJC) codes

Biotechnology
Bioengineering
Biomedical Engineering
Applied Microbiology and Biotechnology
Molecular Medicine

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10.1038/s41587-022-01465-1

Cite this

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title = "Capturing the diversity of protein modifications on presented tumor antigens",

abstract = "Post-translational modifications (PTMs) alter the structure, properties and functions of proteins in all aspects of biology. A new computational pipeline, termed protein modification integrated search engine (PROMISE), reveals the impact these modifications might have on the presentation of cancer antigens to T cells.",

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Capturing the diversity of protein modifications on presented tumor antigens

Abstract

All Science Journal Classification (ASJC) codes

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