Can't smell the virus: SARS-CoV-2, chromatin organization, and anosmia

Matan Sorek; Eran Meshorer

doi:10.1016/j.devcel.2022.04.015

Can't smell the virus: SARS-CoV-2, chromatin organization, and anosmia

Matan Sorek, Eran Meshorer

Department of Genetics

The Hebrew University of Jerusalem

Research output: Contribution to journal › Comment/debate

Abstract

Anosmia, or loss of smell, is strongly associated with SARS-CoV-2 infection in humans, but the underlying mechanism remains obscure. In a recent Cell study, Zazhytska et al. (2022) report non-cell-autonomous disruption of long-range genomic interactions of olfactory receptor genes in response to SARS-CoV-2 infection, and these interactions remain disrupted long after virus clearance.

Original language	English
Pages (from-to)	1081-1082
Number of pages	2
Journal	Developmental Cell
Volume	57
Issue number	9
DOIs	https://doi.org/10.1016/j.devcel.2022.04.015
State	Published - 9 May 2022

All Science Journal Classification (ASJC) codes

Molecular Biology
General Biochemistry,Genetics and Molecular Biology
Developmental Biology
Cell Biology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.devcel.2022.04.015

Cite this

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abstract = "Anosmia, or loss of smell, is strongly associated with SARS-CoV-2 infection in humans, but the underlying mechanism remains obscure. In a recent Cell study, Zazhytska et al. (2022) report non-cell-autonomous disruption of long-range genomic interactions of olfactory receptor genes in response to SARS-CoV-2 infection, and these interactions remain disrupted long after virus clearance.",

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Can't smell the virus: SARS-CoV-2, chromatin organization, and anosmia

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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