@inproceedings{6fb8e7ec29d944419dff4b3fab933e70,
title = "Can we make porous silicon biosensors more sensitive? Modeling and limitations",
abstract = "We present a mathematical model, which describes the complex mass transport phenomena and reaction kinetics in porous silicon (PSi) optical transducers, and reveal that the interrelated effect of bulk and hindered diffusion is the main limiting factor in these biosensing schemes. Thus, without significantly accelerating the mass transport to and within the nanostructure, the target capture performance of these biosensors would be comparable, regardless of the nature of the capture probe-target pair. Based on the model results, we suggest rules of thumb for increasing their performance.",
keywords = "Aptamer, Biosensor, Hindered diffusion, Mass transfer, Porous silicon",
author = "Sofia Arshavsky-Graham and Evgeniy Boyko and Rachel Salama and Ester Segal",
note = "Publisher Copyright: {\textcopyright} 2020 CBMS-0001; 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020 ; Conference date: 04-10-2020 Through 09-10-2020",
year = "2020",
language = "الإنجليزيّة",
series = "MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences",
pages = "613--614",
booktitle = "MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences",
}