c-Abl activates RIPK3 signaling in Gaucher disease

Keyphrases

• Gaucher Disease 100%
• Receptor-interacting Protein Kinase 3 (RIPK3) 100%
• C-Abl 100%
• Disease Model 16%
• Imatinib 8%
• Phosphorylation 8%
• Tyrosine 8%
• Parkinson's Disease 8%
• Mouse Model 8%
• Cell Death 8%
• Therapeutic Approaches 8%
• Patient Fibroblasts 8%
• Neurological Symptoms 8%
• Pharmacological Inhibitors 8%
• Null Mice 8%
• Homozygous mutation 8%
• Genetic Risk 8%
• Necrosis 8%
• Phosphorylated Forms 8%
• Necroptosis 8%
• FDA-approved Drugs 8%
• Genetic Ablation 8%
• Downstream Signaling 8%
• GBA1 Gene 8%
• α-glucosidase 8%
• Direct Induction 8%
• Abl Tyrosine Kinase 8%
• Indirect Function 8%
• Visceral Symptoms 8%

Biochemistry, Genetics and Molecular Biology

• Gaucher's Disease 100%
• RIPK3 100%
• Enzyme 8%
• Kinase 8%
• Phosphotransferase 8%
• Tyrosine 8%
• Fibroblast 8%
• Mouse Model 8%
• Cell Death 8%
• Imatinib 8%
• Receptor Tyrosine Kinase 8%
• Tyrosine Kinase 8%
• Knockout Mouse 8%
• Genetic Risk 8%
• Necroptosis 8%
• Genetic Ablation 8%
• Glucosidase 8%