Butyrate Makes Macrophages “Go Nuclear” against Bacterial Pathogens

Lior Lobel; Wendy S. Garrett

doi:10.1016/j.immuni.2019.01.015

Butyrate Makes Macrophages “Go Nuclear” against Bacterial Pathogens

Lior Lobel, Wendy S. Garrett

Research output: Contribution to journal › Short survey › peer-review

Abstract

Butyrate is a microbial metabolite with pleiotropic effects. Schulthess et al. (2019) report that butyrate preconditioning of macrophages enhances their anti-bacterial preparedness by inducing anti-microbial proteins that restrict bacterial growth. This study augments understanding of how microbial metabolites shape host defense.

Original language	English
Pages (from-to)	275-278
Number of pages	4
Journal	Immunity
Volume	50
Issue number	2
DOIs	https://doi.org/10.1016/j.immuni.2019.01.015
State	Published - 19 Feb 2019
Externally published	Yes

All Science Journal Classification (ASJC) codes

Immunology and Allergy
Immunology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.immuni.2019.01.015

Cite this

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title = "Butyrate Makes Macrophages “Go Nuclear” against Bacterial Pathogens",

abstract = "Butyrate is a microbial metabolite with pleiotropic effects. Schulthess et al. (2019) report that butyrate preconditioning of macrophages enhances their anti-bacterial preparedness by inducing anti-microbial proteins that restrict bacterial growth. This study augments understanding of how microbial metabolites shape host defense.",

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AU - Garrett, Wendy S.

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AB - Butyrate is a microbial metabolite with pleiotropic effects. Schulthess et al. (2019) report that butyrate preconditioning of macrophages enhances their anti-bacterial preparedness by inducing anti-microbial proteins that restrict bacterial growth. This study augments understanding of how microbial metabolites shape host defense.

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Butyrate Makes Macrophages “Go Nuclear” against Bacterial Pathogens

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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