Brain Organization and Human Diseases

Tamar Sapir, Dalit Sela-Donenfeld, Maayan Karlinski, Orly Reiner

Research output: Contribution to journalArticlepeer-review

Abstract

The cortex is a highly organized structure that develops from the caudal regions of the segmented neural tube. Its spatial organization sets the stage for future functional arealization. Here, we suggest using a developmental perspective to describe and understand the etiology of common cortical malformations and their manifestation in the human brain.
Original languageEnglish
Article number1642
Number of pages19
JournalCells (Basel, Switzerland)
Volume11
Issue number10
DOIs
StatePublished - 14 May 2022

Keywords

  • cortical development
  • forebrain
  • holoprosencephaly
  • lissencephaly
  • neuronal migration
  • signaling factors
  • telencephalon

All Science Journal Classification (ASJC) codes

  • General Biochemistry,Genetics and Molecular Biology

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