Abstract
Herein, we present the formation of acyclic frameworks bearing two consecutive stereocenters of either tertiary or quaternary nature starting from easily accessible cyclopropenes. This holistic approach involves a regio- and diastereoselective hydro- or carboborylation of substituted cyclopropenyl esters. Formation of boronate complexes of the latter via the addition of nucleophiles and subsequent stereospecific 1,2-migration with carbon-carbon bond cleavage delivered the title compounds.
Original language | English |
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Pages (from-to) | 16298-16302 |
Number of pages | 5 |
Journal | Journal of the American Chemical Society |
Volume | 144 |
Issue number | 36 |
DOIs | |
State | Published - 14 Sep 2022 |
All Science Journal Classification (ASJC) codes
- General Chemistry
- Biochemistry
- Catalysis
- Colloid and Surface Chemistry