Biosensors with nuclear tracks and embedded membranes

D. Fink, J. Vacik, H. García Arellano, H. G. Muñoz, L. Alfonta, W. R. Fahrner, K. Hoppe, A. Kiv

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


One of the strategies for enhancing the detection sensitivity of etched nuclear track-based biosensors uses the cladding of track walls with enzymes and the subsequent enrichment of charged enzymatic reaction products in the confined volume of the narrow tracks. For sensing two different bio-molecule types simultaneously, the tracks can be separated into two adjacent compartments by inserting a membrane in between them. The recipe for membrane formation is outlined. If the same enzyme is inserted into both compartments, the sensing accuracy can greatly be enhanced, as compared to etched tracks without membranes, due to a different underlying sensing mechanism. Such sensors act as frequency filters, which is useful for sensors operating in electrosmog-rich ambient.

Original languageEnglish
Title of host publicationMaterials and Applications for Sensors and Transducers III
Number of pages4
StatePublished - 1 Jan 2014
Event3rd International Conference on Materials and Applications for Sensors and Transducers, IC-MAST 2013 - Prague, Czech Republic
Duration: 13 Sep 201317 Sep 2013

Publication series

NameKey Engineering Materials


Conference3rd International Conference on Materials and Applications for Sensors and Transducers, IC-MAST 2013
Country/TerritoryCzech Republic


  • Biosensors
  • Coupled chemical reactions
  • Enzymes
  • Etching
  • Ion irradiation
  • Membranes
  • Nuclear tracks
  • Polymers
  • Precipitation

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering


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