Abstract
One of the strategies for enhancing the detection sensitivity of etched nuclear track-based biosensors uses the cladding of track walls with enzymes and the subsequent enrichment of charged enzymatic reaction products in the confined volume of the narrow tracks. For sensing two different bio-molecule types simultaneously, the tracks can be separated into two adjacent compartments by inserting a membrane in between them. The recipe for membrane formation is outlined. If the same enzyme is inserted into both compartments, the sensing accuracy can greatly be enhanced, as compared to etched tracks without membranes, due to a different underlying sensing mechanism. Such sensors act as frequency filters, which is useful for sensors operating in electrosmog-rich ambient.
Original language | English |
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Title of host publication | Materials and Applications for Sensors and Transducers III |
Pages | 83-86 |
Number of pages | 4 |
DOIs | |
State | Published - 1 Jan 2014 |
Event | 3rd International Conference on Materials and Applications for Sensors and Transducers, IC-MAST 2013 - Prague, Czech Republic Duration: 13 Sep 2013 → 17 Sep 2013 |
Publication series
Name | Key Engineering Materials |
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Volume | 605 |
Conference
Conference | 3rd International Conference on Materials and Applications for Sensors and Transducers, IC-MAST 2013 |
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Country/Territory | Czech Republic |
City | Prague |
Period | 13/09/13 → 17/09/13 |
Keywords
- Biosensors
- Coupled chemical reactions
- Enzymes
- Etching
- Ion irradiation
- Membranes
- Nuclear tracks
- Polymers
- Precipitation
All Science Journal Classification (ASJC) codes
- Materials Science(all)
- Mechanics of Materials
- Mechanical Engineering